Overview

The proceedings of a one-day symposium held in Chicago, USA, on November 6, 1997, provide an update for hepatologists, gastroenterologists, and basic scientists with an interest in primary biliary cirrhosis. New insights into the pathogenesis and the natural history of the disease are discussed, and approaches to management of the complications as well as newer therapeutic options are presented.

Full Product Details

Author:   Keith D. Lindor ,  E. Jenny Heathcote ,  Raoul E. Poupon
Publisher:   Springer
Imprint:   Springer
Edition:   1998 ed.
Dimensions:   Width: 15.50cm , Height: 1.20cm , Length: 23.50cm
Weight:   0.980kg
ISBN:  

9780792387404

ISBN 10:   0792387406
Pages:   176
Publication Date:   30 April 1998
Audience:   College/higher education ,  Professional and scholarly ,  Undergraduate ,  Postgraduate, Research & Scholarly
Format:   Hardback
Publisher's Status:   Active
Availability:   In Print  
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Table of Contents

Section I: Natural History and Pathogenesis.- 1 Natural history and demography of primary biliary cirrhosis.- 2 Immune basis for PBC.- 3 Isolation and cloning of antimitochondrial antibodies.- 4 Significance of antimitochondrial antibody profiles in primary biliary cirrhosis.- 5 Chloride/bicarbonate exchange in PBC: a clue for pathogenesis?.- 6 Molecular considerations of primary biliary cirrhosis.- 7 Animal models of primary biliary cirrhosis.- 8 Fibrogenesis in PBC.- 9 Natural history models of primary biliary cirrhosis.- Section II: Management of Primary Biliary Cirrhosis.- 10 Portal hypertension in patients with primary biliary cirrhosis.- 11 Management of primary biliary cirrhosis: osteoporosis.- 12 Fatigue in the primary biliary cirrhosis patient.- 13 The pruritus of cholestasis: behavioral studies shed light on its pathogenesis.- 14 Old and new immunosuppressant drugs: mechanisms and potential value.- 15 Methotrexate and colchicine in the treatment of primary biliary cirrhosis.- 16 Corticosteroids in PBC.- 17 Ursodeoxycholic acid treatment of primary biliary cirrhosis: potential mechanisms of action.- 18 Ursodiol and combination therapy.- 19 Primary biliary cirrhosis transplantation and recurrent disease.- 20 New clinical trials in primary biliary cirrhosis: design and endpoints.

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