Overview

According to the International Classification of Headache Disorders (ICHD-2), migraine is a common disabling primary headache disorder manifesting in attacks lasting 4 to 72 hours. Migraine headaches range from moderate to very severe and are sometimes debilitating. Migraine affects 17% of women and 6% of men. The ICHD-2 divides migraine into migraine with aura and migraine without aura. The most common type of migraine, migraine without aura, is defined as a headache that occurs at least five times per month with headaches lasting between 4 and 72 hours (untreated or unsuccessfully treated), and having a minimum number of migraine attributes [two of (a) unilateral location, (b) pulsating quality, (c) moderate or severe pain intensity, (d) aggravated by or causing avoidance of physical activity and one of (a) nausea and/or vomiting, (b) phonophobia or photophobia] and cannot be attributed to another condition. When migraine without aura occurs on 15 or more days per month for at least 3 months and eight of the headaches meet migraine without aura criteria, without medication overuse, the complication of chronic migraine should be diagnosed. This Future Research Needs (FRN) project is a follow up to the Comparative Effectiveness Review (CER),

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9781492204930

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