Overview

Publisher's Note: Products purchased from Third Party sellers are not guaranteed by the publisher for quality, authenticity, or access to any online entitlements included with the product. Understand the clinical application of genetics in ob-gyn practice with this case-based text This up-to-date resource surveys the modern field of genetics and provides you with a practical understanding of its clinical uses. Whether determining who is pre-disposed to disease, howa patient will respond to therapy, or what the optimal cancer treatment might be based on tumor profiles, this is the only guide to help efficiently interpret and utilize genetic data across the full spectrum of ob-gyn clinical scenarios. Practical Genetics for the Ob-Gyn is organized around three central themes: basic genetic principles, clinical applications of ob-gyn practice, and common methods of genetic testing. Opening each chapter is a patient case study that establishes a realistic clinicalcontext for the subsequent genetics-based material addressed.

Full Product Details

Author:   W. Allen Hogge ,  Aleksandar Rajkovic
Publisher:   McGraw-Hill Education - Europe
Imprint:   McGraw-Hill Professional
Dimensions:   Width: 15.20cm , Height: 1.00cm , Length: 22.90cm
Weight:   0.268kg
ISBN:  

9780071797214

ISBN 10:   0071797211
Pages:   192
Publication Date:   16 August 2014
Audience:   Professional and scholarly ,  Professional & Vocational
Format:   Paperback
Publisher's Status:   Active
Availability:   Manufactured on demand  
We will order this item for you from a manufactured on demand supplier.

Table of Contents

I. Basic Genetic Principles 1. Gene Structure and Function 2. Chromosome Structure and Function 3. Patterns of Inheritance a. Mendelian inhereditance (Include clinical examples for each) i. Autosomal dominant ii. Autosomal recessive iii. Co-dominant iv. X-linked b. Non-mendelian inhereditance (include clinical examples) i. Hereditary unstable DNA ii. Imprinting iii. Uniparental disomy iv. Mitochondrial inhereditance v. Germ line mosaicism c. Multifactorial and Polygenic Inhereditance 4. Chromosomal Abnormalities a. Aneuploidy b. Deletion, Duplication, and Inversions II. Clinical Genetics in the Context of Obstetrics and Gynecology 5. Taking a family history 6. Principles of genetic counseling 7. Preconception counseling 8. Screening for genetic disorders in pregnancy 9. Methods of prenatal diagnosis 10. Common fetal malformations diagnosed by ultrasound 11. Gynecologic disorders with a genetic causation 12. Hereditary cancer syndromes 13. Disorders of sexual differentiation 14. Infertility and pregnancy loss III. Methods of Genetic Testing 15. Traditional cytogenetic testing 16. Molecular cytogenetic testing a. Fluorescent in-situ hybridization b. Microarrays 17. Molecular diagnostic testing a. Southern blot analysis b. Polymerase chain reaction c. DNA sequencing d. New approaches to diagnostic testing

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Author Information

W. Allen Hogge, MD, is the Professor and Chair of the Department of Obstetrics, Gynecology, and Reproductive Sciences at the University of Pittsburgh Schools of Health Sciences, Pittsburgh, Pennsylvania. Aleksandar Rajkovic, MD, PhD, is Associate Professor, Department of Obstetrics, Gynecology, and Reproductive Science; and Chief, Division of Genetics, University of Pittsburgh, Pittsburgh, Pennsylvania.

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