Posttranslational Modifications of Proteins

Author:   Christopher T Walsh
Publisher:   Macmillan Learning
ISBN:  

9780974707730


Pages:   500
Publication Date:   01 October 2005
Format:   Hardback
Availability:   Out of stock   Availability explained
The supplier is temporarily out of stock of this item. It will be ordered for you on backorder and shipped when it becomes available.

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Posttranslational Modifications of Proteins


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Full Product Details

Author:   Christopher T Walsh
Publisher:   Macmillan Learning
Imprint:   Roberts & Company Publishers
Dimensions:   Width: 21.10cm , Height: 3.50cm , Length: 25.50cm
Weight:   1.760kg
ISBN:  

9780974707730


ISBN 10:   0974707732
Pages:   500
Publication Date:   01 October 2005
Audience:   General/trade ,  General
Format:   Hardback
Publisher's Status:   No Longer Our Product
Availability:   Out of stock   Availability explained
The supplier is temporarily out of stock of this item. It will be ordered for you on backorder and shipped when it becomes available.

Table of Contents

Preface 1 Introduction 2 Phosphorylation and dephosphorylation 3 Sulfurylation of proteins 4 Sulfur redox transformations in proteins 5 Protein methylation 6 Protein acetylation 7 Lipid modifications of proteins 8 Posttranslational proteolysis 9 Ubiquitin and ubiquitin like protein tags 10 Protein glycosylation 11 ADP ribosylation of proteins 12 Protein hydroxylation 13 Automodification reactions of proteins 14 Swinging arms for covalent tethering of coenzymes 15 Protein carboxyaltion and amidation References Index

Reviews

Christopher Walsh, an acclaimed scientist, has written yet another outstanding book. It surveys the vast field of chemical modifications that proteins undergo in living cells. The book's depth of coverage and clarity of exposition will make it an indispensable text for both students and active researchers. -- Alexander Varshavsky Smits Professor of Cell Biology, California Institute of Technology Walsh effectively covers all of the major PTMs with a care for detail that is both admirable and captivating. The enzymes involved in generating PTMs are described with clarity and sufficient detail so that both novices and experts in this field are sure to learn much from this book. -- Benjamin F. Cravatt III The Skaggs Institute for Chemical Biology, The Scripps Research Institute Walsh has coalesced the dizzying array of posttranslational modifications into a small subset of reactions. It is written with a concise chemical logic and Walsh's typical flair that makes it a pleasure to read. -- Michael A. Marletta Professor of Chemistry, Professor of Biochemistry and Molecular Biology, University of California, Berkeley


Author Information

Professor Walsh is currently the Hamilton Kuhn Professor of Biological Chemistry and Molecular Pharmacology at Harvard Medical School. He is one of the leading enzymologists in the world. He has published over 600 scientific articles and his book, Enzymatic Reaction Mechanisms (WH Freeman), has educated generations of enzymologists.

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