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OverviewFull Product DetailsAuthor: Margarita Dominguez-VillarPublisher: Springer International Publishing AG Imprint: Springer International Publishing AG Edition: 1st ed. 2022 Volume: 436 Weight: 0.724kg ISBN: 9783031065682ISBN 10: 3031065689 Pages: 466 Publication Date: 17 October 2023 Audience: Professional and scholarly , Professional & Vocational Format: Paperback Publisher's Status: Active Availability: Manufactured on demand  We will order this item for you from a manufactured on demand supplier. Table of ContentsClass I PI3K biology.- Class II PI3K biology.- Class III PI3K biology.- PTEN in immunity.- PHLPP Signaling in Immune Cells.- PHLPP Signaling in Immune Cells.- PI3K isoforms in cell signalling and innate immune cell responses.- AKT isoforms in macrophage activation, polarization and survival.- Control of CD4+ T cell Differentiation and Function by PI3K isoforms..- PI3K isoforms in CD8+ T cell development and function.- PI3K isoforms in B cells.- PI3K isoform signalling in platelets.- PI3K isoforms in vascular biology, a focus on the vascular system-immune response connection.- PI3K and AKT at the Interface of Signaling and Metabolism.- The Role of PI3K Isoforms in Autoimmune Disease.- AKT Isoforms in the Immune Response in Cancer.- PI3K isoform immunotherapy for solid tumours.- PI3K targeting in non-solid cancer.- AKT isoforms as a target in cancer and immunotherapy.- Developing PI3K Inhibitors for Respiratory Diseases.ReviewsAuthor InformationMargarita Dominguez-Villar is a Senior Lecturer in Immunology at Imperial College London. Her research interests focus on the understanding of the mechanisms that regulate T cell responses and regulatory T cell function in health and disease, with a particular focus on autoimmunity and infectious diseases and the role of the PI3K/AKT pathway in controlling these processes. Tab Content 6Author Website:Countries AvailableAll regions |
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