Physical Principles in Sensing and Signaling: With an Introduction to Modeling in Biology

Author:   Robert G. Endres (Reader in Systems Biology, Imperial College London)
Publisher:   Oxford University Press
ISBN:  

9780199600649


Pages:   158
Publication Date:   10 January 2013
Format:   Paperback
Availability:   To order   Availability explained
Stock availability from the supplier is unknown. We will order it for you and ship this item to you once it is received by us.

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Physical Principles in Sensing and Signaling: With an Introduction to Modeling in Biology


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Author:   Robert G. Endres (Reader in Systems Biology, Imperial College London)
Publisher:   Oxford University Press
Imprint:   Oxford University Press
Dimensions:   Width: 19.00cm , Height: 0.80cm , Length: 24.50cm
Weight:   0.362kg
ISBN:  

9780199600649


ISBN 10:   0199600643
Pages:   158
Publication Date:   10 January 2013
Audience:   College/higher education ,  Undergraduate
Format:   Paperback
Publisher's Status:   Active
Availability:   To order   Availability explained
Stock availability from the supplier is unknown. We will order it for you and ship this item to you once it is received by us.

Table of Contents

1: Preface 2: Introduction 3: Physical concepts 4: Mathematical tools 5: Chemotaxis in bacterium Escherichia coli 6: Signal amplification and integration 7: Robust precise adaptation 8: Polar receptor localization and clustering 9: Accuracy of sensing 10: Motor impulse response 11: Optimization of pathway 12: 'Seeing' like a bacterium 13: Beyond E. coli chemotaxis

Reviews

This book organizes and communicates an amazing amount of biophysics using bacterial chemotaxis as an organizing theme. Endres, a leading researcher in cell signaling, writes in an accessible way and coherently covers a vast range of topics - e.g. diffusion, noise, allostery, membrane energetics, information theory, optimization - with crossover appeal to biologists, physicists, and engineers. This work is ideal for senior undergraduates or graduate students with an interest in the exploding field of quantitative biology. Ned Wingreen, Molecular Biology Department, Princeton University


Author Information

At Imperial College Robert Endres heads the Biological Physics Group. Recently he won the prestigious ERC Strating Grant award. Before moving to the United Kingdom, Robert was a postdoc with Prof. Ned Wingreen in the Molecular Biology Department at Princeton University, where his main research accomplishments were the understanding of the remarkable signalling properties of bacterial chemotaxis and the atomistic prediction of protein-DNA binding sites.

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