Overview

This detailed book explores protocols with the aim of testing aerobic exercise, resistance training, special diets, additives and natural products, which have led to new insights into the physiological and molecular aspects of health and disease. Many of these approaches have contributed to significant improvements in disease areas such as cardiovascular disease, cognitive dysfunction, diabetes, frailty, gliobastoma, metabolic syndrome, obesity, oxidative stress, and various cancers. This collection also provides important information on disease mechanisms and novel drug targets as each protocol is presented in the context of specific chronic diseases or different therapeutic areas. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials, step-by-step, readily reproducible protocols, and tips on troubleshooting and avoiding known pitfalls.  Authoritative and reflective of research from all around the globe, Physical Exercise and Natural and Synthetic Products in Health and Disease serves as an ideal guide for researchers in the areas of chronic disease, exercise, and nutrition, as well as to clinical scientists, physicians, and pharmacologists as it gives insights into possibilities for the development of novel therapeutics and the means of monitoring therapeutic response through the measurement of molecular and physiometric biomarkers.

Full Product Details

Author:   Paul C. Guest
Publisher:   Springer-Verlag New York Inc.
Imprint:   Springer-Verlag New York Inc.
Edition:   1st ed. 2022
Volume:   2343
Weight:   0.795kg
ISBN:  

9781071615607

ISBN 10:   1071615602
Pages:   403
Publication Date:   04 September 2022
Audience:   Professional and scholarly ,  Professional & Vocational
Format:   Paperback
Publisher's Status:   Active
Availability:   Manufactured on demand  
We will order this item for you from a manufactured on demand supplier.

Table of Contents

Part I: Reviews   1. The New Frontier of Three-Dimensional Culture Models to Scale Up Cancer Research‎             Caleb Jensen, Chloe Shay, and Yong Teng   2. Therapeutic Effects of Resveratrol on Non-Alcoholic Fatty Liver Disease through Inflammatory, Oxidative Stress, Metabolic, and Epigenetic Modifications             Mina Karimi, Behnaz Abiri, Paul C. Guest, and Mohammadreza Vafa   3. A Matter of Fat: Body Fat Distribution and Cardiometabolic Disease in Africa             Nasrin Goolam Mahyoodeen and Nigel J. Crowther   4. PGK1: An Essential Player in Modulating Tumor Metabolism             Leslie Duncan, Chloe Shay, and Yong Teng   5. The Association of Reproductive Aging with Cognitive Function in Sub-Saharan African Women             Nicole G. Jaff and Nigel J. Crowther   6. The Effects of Exercise on Lipid Biomarkers             Michael F. Mendoza, Sergey M. Kachur, and Carl J. Lavie   7. Exercise Training Protocols to Improve Obesity, Glucose Homeostasis, and Subclinical Inflammation             Tiego A. Diniz, Barbara M. Antunes, Jonathan P. Little, Fabio S. Lira, and José Cesar Rosa-Neto   Part II: Protocols   8. A Protocol of Intradialytic Exercise for Improvements in Inflammatory Status, Body Composition, and Functional Capacity             Lorena Cristina Curado Lopes, Paula Alves Monteiro, and João Felipe Mota   9. Evaluating the Anticancer Activity of Natural Products Using a Novel 3D Culture Model             Chloe Shay and Yong Teng   10. Evaluation of Antidiabetic Properties of Adenosma bracteosum Bonati Extracts in Mice with Streptozotocin-Induced Diabetes             Giau Van Vo, Paul C. Guest, and Ngoc Hong Nguyen   11. Testing the Effects of Cinnamon Extract Supplementation on Inflammation and Oxidative Stress Induced by Acrylamide             Fatemeh Haidari, Majid Mohammadshahi, Behnaz Abiri, Paul C. Guest, Mehdi Zarei, and Mojdeh Fathi   12. Proteomic Mapping of the Human Myelin Proteome             Paul C. Guest   13. Testing for Thyroid Peroxidase and Anti-Neuronal Antibodies in Depression and Schizophrenia             Johann Steiner, Winfried Stoecker, Bianca Teegen, Henrik Dobrowolny, Gabriela Meyer-Lotz, Katrin Borucki, Paul C. Guest, and Hans-Gert Bernstein   14. Evaluation of Antimicrobial and Anticancer Activities of Bouea macrophylla Ethanol Extract             Giau Van Vo, Paul C. Guest, and Ngoc Hong Nguyen   15. Evaluation of Anti-Hepatocellular-Cancer Properties of β-Sitosterol and β-Sitosterol-Glucoside from Indigofera zollingeriana Miq             Giau Van Vo, Paul C. Guest, Thuy Trang Nguyen, and Tuong Kha Vo   16. Label-Free Electrochemical Biosensors to Evaluate the Antioxidant Effect of Tocopherol in Ultraviolet Radiation             Lixia Gao and Yong Teng   17. qRT-PCR Analysis of GLUT-4 and Assessment of Trolox as an Effective Antioxidant in Diabetic Cardiomyoblasts             S. Asha Devi, Ravichandra Shivalingappa Davargaon, and Subramanyam Muthangi VV   18. Flow Cytometric Analysis of Hyperglycemia-Induced Cell Death Pathways in Cardiomyoblasts             Ravichandra Shivalingappa Davargaon, Subramanyam Muthangi VV, and S. Asha Devi   19. Vietnamese Medicinal Plants as Potential Resources to Explore New Anti-Cancer and Anti-Inflammation: Established Assays for Pharmacological Tests             Trang Thi Phuong Nguyen, Dieu Thi Xuan Nguyen, and Triet Thanh Nguyen   20. Testing the Effect of Curcumin on Proliferative Capacity of Colorectal Cancer Cells             Tannaz Jamialahmadi, Paul C. Guest, Amir R. Afshari, Muhammed Majeed, and Amirhossein Sahebkar   21. Assessment of Topical and Transdermal Penetration of Curcuma heyneana Rhizome Extract in Rat Skin: Histological Analysis             Idha Kusumawati, Rohmania, Mega Ferdina Warsito, and Eka Pramyrtha Hestianah   22. Measuring the Effects of Berberine on Serum Pro-Oxidant–Antioxidant Balance in Metabolic Syndrome             Tannaz Jamialahmadi, Paul C. Guest, Aida Tasbandi, Khalid Al-Rasadi, and Amirhossein Sahebkar   23. Testing the Anti-Inflammatory Effects of Curcuminoids in Patients with Colorectal Cancer             Tannaz Jamialahmadi, Paul C. Guest, Aida Tasbandi, Muhammed Majeed, and Amirhossein Sahebkar   24. Analytical Methods and Bioassays for Cytotoxicity and Anti-Diabetic Properties of Aquilaria Crassna Leaf Extracts in HepG2 Cells             Pinnara Rojvirat, Netiya Karaket, Phanupol Mongkolsiri, and Sarawut Jitrapakdee   25. Testing the Physical and Molecular Effects of Nutritional Supplements and Resistance Exercise in Middle-Aged Females             Behnaz Abiri, Paul C. Guest, Parvin Sarbakhsh, and Mohammadreza Vafa   26. Analysis of Cytotoxic Effects of Zerumbone in Malignant Glioblastoma Cells             Mohammad Jalili-Nik, Amir R. Afshari, Khadijeh Mahboobnia, Paul C. Guest, Tannaz Jamialahmadi, and Amirhossein Sahebkar   27. Protocol for Testing the Potential Antioxidant Effects of Curcuminoids on Patients with Type 2 Diabetes Mellitus             Tannaz Jamialahmadi, Yunes Panahi, Muhammed Majeed, Paul C. Guest, and Amirhossein Sahebkar   28. The Detection of Toxic Compounds in Extracts of Callilepis laureola (Ox-Eye Daisy) and Senecio latifolius (Ragwort) by Ultra-Performance Liquid Chromatography Mass Spectrometry (UPLC-MS/MS)             Tracy Snyman and Nigel J. Crowther   29. Impact of Curcumin on Hepatic Low-Density Lipoprotein Uptake             Mohammad Jalili-Nik, Khadijeh Mahboobnia, Paul C. Guest, Muhammed Majeed, Khalid Al-Rasadi, Tannaz Jamialahmadi, and Amirhossein Sahebkar

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