Phenotypic Screening: Methods and Protocols

Author:   Bridget Wagner
Publisher:   Humana Press Inc.
Edition:   Softcover Reprint of the Original 1st 2018 ed.
Volume:   1787
ISBN:  

9781493993031


Pages:   280
Publication Date:   10 December 2019
Format:   Paperback
Availability:   Manufactured on demand   Availability explained
We will order this item for you from a manufactured on demand supplier.

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Phenotypic Screening: Methods and Protocols


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Author:   Bridget Wagner
Publisher:   Humana Press Inc.
Imprint:   Humana Press Inc.
Edition:   Softcover Reprint of the Original 1st 2018 ed.
Volume:   1787
Weight:   0.559kg
ISBN:  

9781493993031


ISBN 10:   1493993038
Pages:   280
Publication Date:   10 December 2019
Audience:   Professional and scholarly ,  Professional & Vocational
Format:   Paperback
Publisher's Status:   Active
Availability:   Manufactured on demand   Availability explained
We will order this item for you from a manufactured on demand supplier.

Table of Contents

Nutrient Stress Small-Molecule Screening Platform for Escherichia coli.- Validation and Development of an Escherichia coli Riboflavin Pathway Phenotypic Screen Hit as a Small-molecule Ligand of the Flavin Mononucleotide Riboswitch.- Phenotypic Screening of Small Molecules with Anti-malarial Activity for Three Different Parasitic Life Stages.- Phenotypic Screening for Inhibitors of a Mutant Thrombopoietin Receptor.- A cell-based Assay for Mitotic Spindle Orientation.- Isolation of Skeletal Muscle Stem Cells for Phenotypic Screens for Modulators of Proliferation.- Cell-based Methods to Identify Inducers of Human Pancreatic Beta-cell Proliferation.- High-content Imaging Phenotypic Screen for Neurogenesis Using Primary Neural Progenitor Cells.- Discovery of Modulators of Adipocyte Physiology Using Fully Functionalized Fragments.- The Ancient Genetic Networks of Obesity: Whole-animal Automated Screening for Conserved Fat Regulators.- Modulation of Threat Response in Larval Zebrafish.- A PLA-iRoCS Pipeline for the Localization of Protein-Protein Interactions in situ.- High-Dimensional Profiling: The Theta Comparative Cell Scoring Method.- Accessing the Open PHACTS Discovery Platform with workflow tools.- Quantitative Prioritization of Tool Compounds for Phenotypic Screening.- A Quantitative Systems Pharmacology Approach to Infer Pathways Involved in Complex Disease Phenotypes.- Phenotype-based High-content Screening using Fluorescent Chemical Bioprobes: Lipid Droplets and Glucose Uptake Quantification in Live Cells.- Developing High-throughput Electrophysiological Assays for Phenotypic Screening.- Testing Susceptibility of Patient Derived Organoid Cultures to Therapies: Pharmacotyping.- Techniques to Enable 1536-well Phenotypic Screening. 

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