Overview

Understand the nature and applications of peptides with this clear and comprehensive guide Peptides are signaling molecules comprised of amino acids which play an important role in modulating certain physiological processes. They have a wide range of applications, particularly with respect to biological studies and therapeutical potentials. The explosive growth of peptide science in recent years and the variety of achievements in peptide drug discovery and related areas have made it an important area of study for new researchers and industry professionals. Peptide Science offers a clear, systematic overview of this burgeoning field and its major applications. Covering the chemistry, the pertinent technologies, and major existing therapies, it provides the tools required to integrate peptide research with virtually any area of research and development. Fully cognizant of the latest technological advances, it’s a must-own for anyone looking to understand a vital field of chemistry. Peptide Science readers will also find: Through coverage of peptide hit generation technologies from nature, to various display libraries and to modern computational designs Detailed discussion of therapies for conditions including cancer, diabetes, infectious diseases, and more A section dedicated to key challenges and future directions in peptide therapeutics Peptide Science is ideal for industry professionals and researchers in organic chemistry, peptide science/chemistry, protein chemistry, biochemistry, and pharmaceutical sciences.

Full Product Details

Author:   Fa Liu (Shanghai Institute of Organic Chemistry, CAS, China)
Publisher:   John Wiley & Sons Inc
Imprint:   John Wiley & Sons Inc
Weight:   1.021kg
ISBN:  

9781119824671

ISBN 10:   1119824672
Pages:   544
Publication Date:   15 July 2025
Audience:   Professional and scholarly ,  Professional & Vocational
Format:   Hardback
Publisher's Status:   Active
Availability:   Out of stock  
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Table of Contents

CONTENTS     Preface List of contributors   Section I. New Development in Peptide Chemistry Chapter 1. Chemical Peptide Ligations Chapter 2. Protein and Peptide Ligation Using Peptide Ligases Chapter 3. Modern Methods for Late-Stage Peptide Modification   Section II. Peptide Drug Hit Identification Chapter 4. From Natural Products to Peptide Drugs Chapter 5. Generating Phage Libraries Bearing Unnatural Pharmacophores Chapter 6. Computational Peptide Design for Diverse Structures and Functions   Section III. Peptide Drug Lead Generation and Optimization Chapter 7. Peptide Discovery: Lead Generation Chapter 8. A Survey and Guide to the Development of Fatty Acid-Derivatized Peptide Therapeutics   Section IV. Peptide Drug Case Studies Chapter 9. Insulin In Its Second Century: History, Evolution and Aspirations Chapter 10. Incretins and Development of Incretin-based Therapeutics Chapter 11. Peptide-Based Therapeutics for Inflammatory and Autoimmune Diseases Chapter 12. Radioligand as a Unique Rising Modality for Cancer Diagnosis and Treatment Chapter 13. Peptide-Small Molecule Drug Conjugates for Cancer, Metabolic Diseases and Beyond Chapter 14. Emerging Landscape of Therapeutic Oligonucleotide Delivery by Cell-Penetrating Peptide   Section V. Peptide CMC and Regulatory Chapter 15. Peptide Chemistry, Manufacturing and Controls  

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Author Information

Fa Liu, PhD, is the CSO of Full-Life Technologies, which centers on targeted alpha-radionuclide therapies. Prior to joining Full-Life, he was the CEO and Co-founder of Focus-X Therapeutics (2020-2022), later acquired by Full-Life. Before founding Focus-X, Dr. Liu headed the Chemistry of Novo Nordisk US sites, and Calibrium LLC (acquired by Novo Nordisk) (2014-2020), and served as a Group Leader at the Eli Lilly Peptide Discovery (2009-2014). Prior to Lilly, Dr. Liu worked at National Cancer Institute as a Staff Scientist (2004-2009). He received his Ph.D. in Synthetic Organic Chemistry from Shanghai Institute of Organic Chemistry in 2004.

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