Overview

Rubin and Damjanov's latest volume of Pathology Reviews highlights the latest progress in the interface of biology and disease. Forefront techniques and experimental models that were once considered exotic or esoteric, are explored here in the context of understanding more fully the processes involved in human disease. Topics include: regulation of liver growth * contractile cells in lungs * mineral formation in bone * folate metabolism * the ""riddle of the mast cell"" * HLA antigens * interleukin 6 * IgA nephropathy * Goodpasture syndrome * anti-basement membrane glomerulonephropathy * molecular mechanisms of oncogenesis * molecular diagnosis of cancer * inhibition of intercellular communication in carcinogenesis * DNA repair and its pathogenetic implications * human and rat mammary tumorigenesis. Pathology Reviews * 1990 is essential reading for everyone concerned with the mechanisms of disease.

Full Product Details

Author:   Ivan Damjanov ,  Emanuel Rubin
Publisher:   Humana Press Inc.
Imprint:   Humana Press Inc.
Edition:   Softcover reprint of the original 1st ed. 1990
Dimensions:   Width: 21.00cm , Height: 1.40cm , Length: 28.00cm
Weight:   0.667kg
ISBN:  

9781461267836

ISBN 10:   1461267838
Pages:   255
Publication Date:   08 October 2012
Audience:   Professional and scholarly ,  Professional & Vocational
Format:   Paperback
Publisher's Status:   Active
Availability:   Manufactured on demand  
We will order this item for you from a manufactured on demand supplier.

Table of Contents

Section I: Cell and Metabolic Disorders.- Regulation of Liver Growth: Protooncogenes and Transforming Growth Factors.- Mechanism of Mineral Formation in Bone.- Contractile Cells in Normal and Fibrotic Lungs.- Role of Folate Binding Proteins in Folate Metabolism.- New Insights into “The Riddle of the Mast Cells”: Microenvironmental Regulation of Mast Cell Development and Phenotypic Heterogeneity.- Section II: Inflammation and Immunity.- HLA Class II Polymorphism: Implications for Genetic Susceptibility to Autoimmune Disease.- Interleukin 6: A Multifunctional Cytokine Regulating Immune Reactions and the Acute Phase Protein Response.- IgA Nephropathy: Pathogenesis of the Most Common Form of Glomerulonephritis.- Goodpasture Syndrome: Molecular Architecture and Function of Basement Membrane Antigen.- Pathogenesis of Anti-Basement Membrane Glomerulopathy and Immune-Complex Glomerulonephritis: Dichotomy Dissolved.- Section III: Tumor Biology.- Molecular Mechanisms of Oncogenesis.- DNA Repair and Its Pathogenetic Implications.- Molecular Diagnosis of Human Cancer.- Role of Inhibition of Intercellular Communication in Carcinogenesis.- Comparative Study of Human and Rat Mammary Tumorigenesis.

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