Pathogenicity Islands and the Evolution of Pathogenic Microbes: Volume I
Author:   J. Hacker ,  J.B. Kaper
Publisher:   Springer-Verlag Berlin and Heidelberg GmbH & Co. KG
Edition:   Softcover reprint of the original 1st ed. 2002
Volume:   264/2
ISBN:  

9783642627200


Pages:   444
Publication Date:   06 October 2012
Format:   Paperback
Availability:   Manufactured on demand   Availability explained
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Pathogenicity Islands and the Evolution of Pathogenic Microbes: Volume I


Overview

It has been known for a number of years that not only pathogenicity islands but also plasmids and bacteriophages are able to carry genes whose products are involved in pathogenic processes. Accordingly, such elements and their products play an important role in pathogenesis due to the intestinal E. coli as well to Shigellae. Another interesting aspect which is reflected in different articles is that genomes evolve by acquisition of new pieces of DNA following gene transfer, but also by genome reduction. Different mechanisms include the deletion of sequences or the elimination of functions by the accumulation of point mutations or rearrangements.

Full Product Details

Author:   J. Hacker ,  J.B. Kaper
Publisher:   Springer-Verlag Berlin and Heidelberg GmbH & Co. KG
Imprint:   Springer-Verlag Berlin and Heidelberg GmbH & Co. K
Edition:   Softcover reprint of the original 1st ed. 2002
Volume:   264/2
Dimensions:   Width: 15.50cm , Height: 1.30cm , Length: 23.50cm
Weight:   0.392kg
ISBN:  

9783642627200


ISBN 10:   364262720
Pages:   444
Publication Date:   06 October 2012
Audience:   Professional and scholarly ,  Professional & Vocational
Format:   Paperback
Publisher's Status:   Active
Availability:   Manufactured on demand   Availability explained
We will order this item for you from a manufactured on demand supplier.

Table of Contents

List of Contents.- Evolution of Prokaryotic Genomes.- Extraintestinal Escherichia coli as a Model System for the Study of Pathogenicity Islands.- Pathogenicity Islands of Intestinal E. coli.- Pathogenicity Islands of Shigella.- Pathogenicity Islands and Host Adaptation of Salmonella Serovars.- Plasmids and Pathogenicity Islands of Yersinia.- Genomic Organization of LPS-Specific Loci.- Genomic Structure of Capsular Determinants.- Genome Plasticity in Pathogenic and Nonpathogenic Enterobacteria.- Phylogenetic Relationships and Virulence Evolution in the Genus Bordetella.- Pathogenicity Islands and PAI-Like Structures in Pseudomonas Species.

Reviews

From the reviews: This compendium brought together by J. Hacker and J. B. Kaper as editors, features an international assembly of authors ... giving a lucid introduction into the evolution of prokaryotic genomes. The ... work provides a comprehensive overview of the current state of knowledge on PAIs and other mobile virulence determinants in bacterial as well as fungal pathogens of humans and plants. (Susanne Rohrer, BioWorld, Issue 61, 2002)


From the reviews: This compendium brought together by J. Hacker and J. B. Kaper as editors, features an international assembly of authors ... giving a lucid introduction into the evolution of prokaryotic genomes. The ... work provides a comprehensive overview of the current state of knowledge on PAIs and other mobile virulence determinants in bacterial as well as fungal pathogens of humans and plants. (Susanne Rohrer, BioWorld, Issue 61, 2002)


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