PAS Proteins: Regulators and Sensors of Development and Physiology
Author:   Stephen T. Crews
Publisher:   Springer-Verlag New York Inc.
Edition:   2003 ed.
ISBN:  

9781402075865


Pages:   263
Publication Date:   30 September 2003
Format:   Hardback
Availability:   Out of stock   Availability explained
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PAS Proteins: Regulators and Sensors of Development and Physiology


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Overview

This volume provides a comprehensive examination of the biochemistry and biology of all classes of known PAS proteins, with the intention that readers will find insight into their own work and ideas from study of the multitude of PAS protein functions. PAS proteins control numerous physiological and developmental events and span phylogeny from bacteria to man. Bacterial and plant PAS proteins act as sensors of environmental stimuli, including light, oxygen and energy status. Not surprising, given these roles, there is intense investigation of the roles of bHLH-PAS proteins in issues of human health including: (1) cancer induction, (2) cancer growth and vascularity, (3) birth defects, including Down syndrome, (4) appetite control and obesity, (5) sleep rhythm disorders and (6) mental health disorders such as social interactions and learning.

Full Product Details

Author:   Stephen T. Crews
Publisher:   Springer-Verlag New York Inc.
Imprint:   Springer-Verlag New York Inc.
Edition:   2003 ed.
Dimensions:   Width: 15.50cm , Height: 2.00cm , Length: 23.50cm
Weight:   0.653kg
ISBN:  

9781402075865


ISBN 10:   1402075863
Pages:   263
Publication Date:   30 September 2003
Audience:   College/higher education ,  Professional and scholarly ,  Undergraduate ,  Postgraduate, Research & Scholarly
Format:   Hardback
Publisher's Status:   Active
Availability:   Out of stock   Availability explained
The supplier is temporarily out of stock of this item. It will be ordered for you on backorder and shipped when it becomes available.

Table of Contents

Structure of the PAS Fold and Signal Transduction Mechanisms.- Signal Transduction in Prokaryotic PAS Domains.- bHLH-PAS Proteins in C. elegans.- Drosophila bHLH-PAS Developmental Regulatory Proteins.- Methoprene-Tolerant, a PAS Gene Critical for Juvenile Hormone Signaling in Drosophila Melanogaster.- The P160 Family of Steroid Hormone Receptor Coactivators.- The Ah Receptor.- The HIF-1 Family of bHLH-PAS Proteins: Master Regulators of Oxygen Homeostasis.- Hormones, Obesity, Learning, and Breathing — The Many Functions of Mammalian Single-Minded Genes.- PAS Proteins in the Mammalian Circadian Clock.

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