Overview

This ambitious collection of essential yet novel methods for pancreatic cancer research or cancer research in general features an outstanding cast of authors who are esteemed leaders in the field. The authors provide a broad range of methods for molecular, biochemical, pathological, and statistical analysis of sporadic and familial pancreatic cancer, methods that can be applied not only to basic, but also to translational pancreatic research. Topics covered include in vitro cell cultures, in vivo mouse models, protein studies, mutation analysis, and treatment development.

Full Product Details

Author:   Gloria H. Su
Publisher:   Humana Press Inc.
Imprint:   Humana Press Inc.
Edition:   2005 ed.
Volume:   103
Dimensions:   Width: 15.50cm , Height: 2.00cm , Length: 23.50cm
Weight:   1.530kg
ISBN:  

9781588291073

ISBN 10:   1588291073
Pages:   352
Publication Date:   12 November 2004
Audience:   College/higher education ,  Professional and scholarly ,  Undergraduate ,  Professional & Vocational
Format:   Hardback
Publisher's Status:   Active
Availability:   In Print  
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Table of Contents

Identification and Analysis of Precursors to Invasive Pancreatic Cancer.- Optimal Molecular Profiling of Tissue and Tissue Components.- Immunohistochemistry and In Situ Hybridization in Pancreatic Neoplasia.- Practical Methods for Tissue Microarray Construction.- Xenografting and Harvesting Human Ductal Pancreatic Adenocarcinomas for DNA Analysis.- Culture and Immortalization of Pancreatic Ductal Epithelial Cells.- DNA Methylation Analysis in Human Cancer.- Digital Single-Nucleotide Polymorphism Analysis for Allelic Imbalance.- Representational Difference Analysis as a Tool in the Search for New Tumor Suppressor Genes.- Serial Analyses of Gene Expression (SAGE).- Oligonucleotide-Directed Microarray Gene Profiling of Pancreatic Adenocarcinoma.- Identification of Differentially Expressed Proteins in Pancreatic Cancer Using a Global Proteomic Approach.- Detection of Telomerase Activity in Patients with Pancreatic Cancer.- Serological Analysis of Expression cDNA Libraries (SEREX).- Modeling Pancreatic Cancer in Animals to Address Specific Hypotheses.- Strategies for the Use of Site-Specific Recombinases in Genome Engineering.- Primary Explant Cultures of Adult and Embryonic Pancreas.- Zebrafish as a Model for Pancreatic Cancer Research.- Development of a Cytokine-Modified Allogeneic Whole Cell Pancreatic Cancer Vaccine.- Overview of Linkage Analysis.

Reviews

.,. a worthwhile contribution from a team of experts. Doody's Health Sciences and Book Review Journal <br> .,. a welcome addition to the field...an excellent collection of protocols for a broad range of advanced techniques relevant to many aspects of pancreatic cancer research. -Karger

""...a worthwhile contribution from a team of experts."" Doody's Health Sciences and Book Review Journal ""...a welcome addition to the field...an excellent collection of protocols for a broad range of advanced techniques relevant to many aspects of pancreatic cancer research."" -Karger

...a worthwhile contribution from a team of experts. Doody's Health Sciences and Book Review Journal ...a welcome addition to the field...an excellent collection of protocols for a broad range of advanced techniques relevant to many aspects of pancreatic cancer research. -Karger

...a worthwhile contribution from a team of experts. Doody's Health Sciences and Book Review Journal ...a welcome addition to the field...an excellent collection of protocols for a broad range of advanced techniques relevant to many aspects of pancreatic cancer research. -Karger

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