p53 Suppressor Gene
Author:   Tapas Mukhopadhyay ,  Steven A. Maxwell ,  Jack A. Roth
Publisher:   Springer-Verlag Berlin and Heidelberg GmbH & Co. KG
Edition:   Softcover reprint of the original 1st ed. 1995
ISBN:  

9783662222775


Pages:   132
Publication Date:   18 April 2014
Format:   Paperback
Availability:   Manufactured on demand   Availability explained
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p53 Suppressor Gene


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Overview

This book is about the p53 gene, one of the most frequently mutated or deleted genes in human cancers. The frequent occurrence of inactivated p53 implicates this gene product in the genesis of many human cancers. The p53 gene can suppress the growth of cancer cells and the transformation process by oncogenes. The p53 protein is a transcription factor that can repress or activate promoters containing one of three p53 DNA-binding motifs. The activity of p53 is regulated by phosphorylation and other transcription factors. Replacement of the p53 function or restoration of the p53 biochemical pathway is a focus of gene therapy.

Full Product Details

Author:   Tapas Mukhopadhyay ,  Steven A. Maxwell ,  Jack A. Roth
Publisher:   Springer-Verlag Berlin and Heidelberg GmbH & Co. KG
Imprint:   Springer-Verlag Berlin and Heidelberg GmbH & Co. K
Edition:   Softcover reprint of the original 1st ed. 1995
Dimensions:   Width: 21.00cm , Height: 0.80cm , Length: 27.90cm
Weight:   0.390kg
ISBN:  

9783662222775


ISBN 10:   3662222779
Pages:   132
Publication Date:   18 April 2014
Audience:   Professional and scholarly ,  Professional & Vocational
Format:   Paperback
Publisher's Status:   Active
Availability:   Manufactured on demand   Availability explained
We will order this item for you from a manufactured on demand supplier.

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