Full Product Details
Author: Rodrigo Franco (University of Nebraska-Lincoln, USA) ,
Jonathan A Doorn (University of Iowa, USA) ,
Jean-Christophe Rochet (Purdue University, USA) ,
Diana Anderson
Publisher: Royal Society of Chemistry
Imprint: Royal Society of Chemistry
Volume: Volume 34
Weight: 0.968kg
ISBN: 9781782621881
ISBN 10: 1782621881
Pages: 536
Publication Date: 25 July 2017
Audience:
Professional and scholarly
,
Professional & Vocational
Format: Hardback
Publisher's Status: Active
Availability: In Print
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Reviews
"""The book should be of interest to all individuals who are interested in PD."" ""With a comprehensive and integrated view on the biology of PD, the Editors and Authors of the book are likely to be instrumental in stimulating a deeper understanding and promoting renewed collaborations on this multifaceted topic, leading to improved understanding of PD."""
The book should be of interest to all individuals who are interested in PD. With a comprehensive and integrated view on the biology of PD, the Editors and Authors of the book are likely to be instrumental in stimulating a deeper understanding and promoting renewed collaborations on this multifaceted topic, leading to improved understanding of PD. -- Michael Aschner Research into the role of oxidative stress and redox signaling in Parkinson's disease (PD) has exploded. A PubMed search (January 8, 2018) identifies 4972 scholarly papers on this topic. Indeed, these are exciting times both for researchers, PD patients and their families. As the human genome has been sequenced and many disease mysteries are unraveled, exciting advances in research on PD have been achieved. Of particular interest in understanding the clinical picture of PD has been the relationship between oxidative stress and the pathophysiology of PD. The Book contains 14 chapters, addressing the topic, research strategies and models aimed at delineating molecular mechanisms of the disease. The typeface is easy to read and the visuals are of great quality. While multi-authored, I generally found all chapters to be up-to-date, providing authoritative reviews of epidemiology, pathology, and neurochemistry. The writing is generally succinct, with discussions pertinent to the topic at hand. The book should be of interest to all individuals who are interested in PD. The Editors should be commended for their efforts to produce a comprehensive, yet easy-to-follow authoritative book on current knowledge in this ever-growing field on PD. The book is successful in bridging basic research with clinical, epidemiological, regulatory and translational research, conveying both an introductory understanding and the latest development in the field. Utmost, it seems to be designed to serve both the novice student and the expert scientist and physician. With a comprehensive and integrated view on the biology of PD, the Editors and Authors the book are likely to be instrumental in stimulating a deeper understanding and promoting renewed collaborations on this multifaceted topic, leading to improved understanding of PD. -- Michael Aschner
Author Information
Dr Franco is an Assistant Professor of Neuroscience at the Redox Biology Center, University of Nebraska-Lincoln. Prior to this position, he was post-doctoral fellow at the National Institute of Environmental Health Sciences, USA. His research interests include the role of oxidative stress and redox signaling in the regulation of cell death pathways, and in neuronal cell death associated with neurological disorders. He has been awarded the Layman Award and the SIGMA XI Outstanding Young Scientist Award. Dr Doorn is an Associate Professor of Medicinal and Natural Products Chemistry at the University of Iowa, College of Pharmacy. Before this, he was a post-doctoral fellow at the University of Colorado Health Sciences Center, Depts. of Pharmaceutical Sciences and Pharmacology, USA. His postdoctoral work involved studying the role of lipid peroxidation products and protein carbonylation in alcoholic liver disease. Dr Doorn received his Ph.D. from the University of Michigan, School of Public Health, Toxicology Program. Dr Rochet is an associate professor in the Department of Medicinal Chemistry and Molecular Pharmacology (College of Pharmacy) at Purdue University. Before his arrival at Purdue, Dr Rochet received his PhD degree at the University of Alberta in Biochemistry in 1998 and then worked as a post-doctoral fellow studying mechanisms of alpha-synuclein self-assembly in Parkinson’s disease in the laboratory of Dr. Peter Lansbury at Harvard Medical School. Dr.Rochet’s research group has a long-standing interest in Parkinson’s disease.
