Overview

Collection of 150 synthetic problems in medicinal chemistry offering mechanistic insights into complex reactions and potential pitfalls in drug synthesis Overcoming Synthetic Challenges in Medicinal Chemistry is a comprehensive collection of around 150 challenging organic reactions in medicinal chemistry, drawn from the author’s work experience and recent journal and patent publications. Problems are arranged by the structure of the reaction product to make it easier for the reader to find the information needed. In this book, readers will find information on: General terms and concepts in synthetic organic chemistry and medicinal chemistry Specific reactions leading to desired products or unexpected side products Step-by-step mechanisms, experimental procedures, literature information, and applications for each reaction Ways to reduce mistakes in synthetic work and optimize product synthesis Overcoming Synthetic Challenges in Medicinal Chemistry serves as a valuable guide for organic chemists, professionals, and job candidates in the pharmaceutical industry, as well as graduates and lecturers at university, helping them grasp complex reactions and gain insight into potential pitfalls and side reactions in drug synthesis.

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9783527355273

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Tongshuang Li has extensive experience in synthetic organic chemistry and medicinal chemistry, with over 22 years in the pharmaceutical industry and 12 years in academia. Currently, he is working as a chemistry consultant for both biotech companies and academics. Dr. Li's work primarily focuses on the synthesis of target compounds for drug discovery, with two new drugs recently approved in China.

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