Overview
A unique guide to variable temperature CD spectroscopy and its application in organic chemistry This timely, original, thought-provoking work looks at organic stereochemistry from the perspective of circular dichroism (CD), using variable temperature CD spectroscopy to determine the conformation or absolute configuration of chiral molecules. With an emphasis on the analysis of optically active ketones and the carbonyl chromophore, the authors demonstrate the advantages of this highly sensitive spectroscopic tool for obtaining stereochemical information in diverse areas of organic chemistry, biochemistry, and medicinal/pharmaceutical chemistry. They combine detailed examples of stereochemical analysis with clear, thorough presentations, correlating chiroptical data with molecular mechanics calculations as well as data from NMR spectroscopy and other spectroscopic techniques. In addition, they provide a systematic survey of the professional literature, featuring an extraordinary collection of original CD spectra run at varying temperatures. Coverage includes: * Chiroptical measurements: CD and ORD (Optical Rotatory Dispersion) * Conformational analysis of compounds ranging from simple cyclic ketones to polycyclics * Conjugated and homoconjugated systems * Stereochemistry of the carbon-carbon double bond * Stereochemistry from exciton coupling of two or more chromophores * An interesting historical account of the development of stereochemical concepts
Full Product Details
Author: David A. Lightner (University of Nevada, Reno, Nevada) ,
Jerome E. Gurst (University of West Florida, Pensacola, Florida) ,
J. E. Guerst (University of West Florida, Pensacola, USA)
Publisher: John Wiley & Sons Inc
Imprint: Wiley-VCH Publishers Inc.,U.S.
Dimensions:
Width: 15.90cm
, Height: 2.90cm
, Length: 23.70cm
Weight: 0.839kg
ISBN: 9780471354055
ISBN 10: 0471354058
Pages: 504
Publication Date: 17 April 2000
Audience:
College/higher education
,
Professional and scholarly
,
Undergraduate
,
Postgraduate, Research & Scholarly
Format: Hardback
Publisher's Status: Active
Availability: Out of stock
The supplier is temporarily out of stock of this item. It will be ordered for you on backorder and shipped when it becomes available.
Reviews
I feel that this book will form a valuable source to all those interested in stereochemistry and conformational analysis of small molecules. This book will very useful... (Talanta, Vol 53, 2001) It is a must for libraries and for all research groups engaged in experimental or theoretical work in this area. (Angewandte Chemie International Edition, Vol. 40 No. 9) ...strongly recommended for research libraries serving organic and pharmaceutical chemists andto some individuals working in those areas. (Journal of the American Chemical Society, Vol. 124, No. 12, 2002)
I feel that this book will form a valuable source to all those interested in stereochemistry and conformational analysis of small molecules. This book will very useful... (Talanta, Vol 53, 2001) It is a must for libraries and for all research groups engaged in experimental or theoretical work in this area. (Angewandte Chemie International Edition, Vol. 40 No. 9) ...strongly recommended for research libraries serving organic and pharmaceutical chemists and...to some individuals working in those areas. (Journal of the American Chemical Society, Vol. 124, No. 12, 2002)
Author Information
DAVID A. LIGHTNER, PhD, is R. C. Fuson Professor of Chemistry at the University of Nevada, Reno. JEROME E. GURST, PhD, is Professor of Chemistry at the University of West Florida, Pensacola.
