Optimized Response-Adaptive Clinical Trials: Sequential Treatment Allocation Based on Markov Decision Problems
Author:   Thomas Ondra
Publisher:   Springer Fachmedien Wiesbaden
Edition:   2015 ed.
ISBN:  

9783658083434


Pages:   102
Publication Date:   18 December 2014
Format:   Paperback
Availability:   Manufactured on demand   Availability explained
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Optimized Response-Adaptive Clinical Trials: Sequential Treatment Allocation Based on Markov Decision Problems


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Full Product Details

Author:   Thomas Ondra
Publisher:   Springer Fachmedien Wiesbaden
Imprint:   Springer Spektrum
Edition:   2015 ed.
Dimensions:   Width: 14.80cm , Height: 0.70cm , Length: 21.00cm
Weight:   1.657kg
ISBN:  

9783658083434


ISBN 10:   3658083433
Pages:   102
Publication Date:   18 December 2014
Audience:   Professional and scholarly ,  Professional & Vocational
Format:   Paperback
Publisher's Status:   Active
Availability:   Manufactured on demand   Availability explained
We will order this item for you from a manufactured on demand supplier.

Table of Contents

​Introduction to Markov Decision Problems and Examples.- Finite and Infinite Horizon Markov Decision Problems.- Solution Algorithms: Backward Induction, Value Iteration and Policy Iteration.- Designing Response Adaptive Clinical Trials with Markov Decision Problems.

Reviews

It is a remarkably concise exposition of the use of MDPs in a pharmaceutical setting; as such, the book's audience is the intersection of researchers and students with a sophisticated mathematical background and professionals in the pharmaceutical industry. ... the book is a very sophisticated treatise on MDP models for managing response-adaptive clinical trials and both mathematicians and pharmaceutical professionals would appreciate it. (James Smith, Interfaces, Vol. 45 (4), July-August, 2015)


“It is a remarkably concise exposition of the use of MDPs in a pharmaceutical setting; as such, the book’s audience is the intersection of researchers and students with a sophisticated mathematical background and professionals in the pharmaceutical industry. … the book is a very sophisticated treatise on MDP models for managing response-adaptive clinical trials and both mathematicians and pharmaceutical professionals would appreciate it.” (James Smith, Interfaces, Vol. 45 (4), July–August, 2015)


Author Information

Thomas Ondra obtained his Master of Science degree in mathematics at University of Vienna. He is a research assistant and PhD student at the Section for Medical Statistics of Medical University of Vienna.

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