Ophthalmic Drug Delivery: Advancement, Industrialization Prospect and Applications

Author:   Neelesh Kumar Mehra, PhD (Senior Research Scientist, Sentiss Research Center, Haryana, India)
Publisher:   Elsevier Science Publishing Co Inc
ISBN:  

9780443337819


Pages:   350
Publication Date:   01 August 2025
Format:   Paperback
Availability:   Not yet available   Availability explained
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Ophthalmic Drug Delivery: Advancement, Industrialization Prospect and Applications


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Overview

Ophthalmic Drug Delivery: Advancement, Industrialization Prospect and Applications delves into the complexities and potential of scaling up and commercializing pharmaceutical innovations within ophthalmology. This book serves as a complete guide through research findings, industry insights, and regulatory guidelines, offering a thorough roadmap for the future of drug delivery systems targeting the eye. The importance of understanding the eye's physiology and anatomy is emphasized, laying the foundational knowledge necessary for developing effective treatments. The book continues by exploring various aspects such as novel formulations, fixed-dose combinations, and microbiological considerations. It also discusses cutting-edge research in reverse engineering approaches, the significance of Quality by Design (QbD), and the treatment of eye-related diseases like glaucoma, age-related macular degeneration, uveal melanoma, cataracts, and fungal keratitis. Corporate researchers will find the manufacturing insights particularly beneficial, making this an essential resource for professionals in the field of ophthalmic drug delivery.

Full Product Details

Author:   Neelesh Kumar Mehra, PhD (Senior Research Scientist, Sentiss Research Center, Haryana, India)
Publisher:   Elsevier Science Publishing Co Inc
Imprint:   Academic Press Inc
ISBN:  

9780443337819


ISBN 10:   0443337810
Pages:   350
Publication Date:   01 August 2025
Audience:   Professional and scholarly ,  Professional & Vocational
Format:   Paperback
Publisher's Status:   Forthcoming
Availability:   Not yet available   Availability explained
This item is yet to be released. You can pre-order this item and we will dispatch it to you upon its release.

Table of Contents

1. Introduction to Ocular Drug Delivery: Core Principles and Fundamental Concepts 2. Complex ophthalmic Drug delivery Approaches 3. Excipients and polymers in complex ophthalmic products: Formulation science and engineering perspectives 4. Fixed-Dose Combination technique in ophthalmic products 5. Emerging trends in ophthalmic products: Microneedles, hydrogels, and ocular inserts 6. Reverse Engineering strategy in Complex Ophthalmic Product 7. Quality by design and Design of Experiments (DOE) in Ophthalmic Product Development: Statistical Approaches and Optimization Strategies 8. Translational roadmap for complex ophthalmic products 9. Manufacturing Consideration, Scale-Up and Validation in Sterile Ophthalmic Formulation 10. Safety Assessment and Toxicological Considerations of Nanocarriers in Ophthalmic Drug Delivery: Risk management, Animal Model and Preclinical Evaluation 11. Advanced packaging, container and closure system for complex ophthalmic products 12. Role of 3D Printing in Ophthalmic Products 13. Stability Studies of Ophthalmic Product 14. Regulatory Landscape of Ophthalmic Products

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Author Information

Neelesh Kumar Mehra is Senior Research Scientist at the Sentiss Research Center, Haryana, India. His area of research is in the design, development, evaluation of ophthalmic nanoemulsion, lipospheres, liposomes, fullerenes, and nanoparticles for topical/parenteral delivery of drugs/biomolecules.

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