Overview
The physical-chemical properties of the omega-3 fatty acid DHA (docosahexaenoic acid) enable it to facilitate rapid biochemical processes in the membrane. This effect has numerous benefits, including those involved in the growth of bacteria, rapid energy generation, human vision, brain impulse, and photosynthesis, to name a few. Yet DHA also carries risks that can lead to cellular death and disease. Omega-3 Fatty Acids and the DHA Principle explores the roles of omega-3 fatty acids in cellular membranes ranging from human neurons and swimming sperm to deep sea bacteria, and develops a principle by which to assess their benefits and risks. The DHA Principle states that the blending of lipids to form cellular membranes is evolutionarily-honed to maximize benefit while minimizing risk, and that a complex blending code involving conformational dynamics, energy stress, energy yield, and chemical stability underlies all cellular membranes. This book lays the groundwork to understanding this code. It examines the evolution of DHA and the membrane and explores the general properties of omega-3s and other membrane lipids. It then focuses on cellular biology before shifting to a practical discussion on applications. The authors discuss the DHA Principle as applied to petroleum degradation, winemaking, global warming, molecular farming, aging, neurodegenerative diseases, and the prevention of colon cancer. Reflecting the increased public interest that has emerged over the years, this volume uses an integrative approach to explain the complex roles of omega-3s in the membrane. Incorporating principles from chemistry, cellular biology, evolution, and ecology, this work gives researchers in a variety of fields the building blocks to stimulate further study.
Full Product Details
Author: Raymond C. Valentine (Professor Emeritus, University of California at Davis, USA) ,
David L. Valentine (University of California, Santa Barbara, USA)
Publisher: Taylor & Francis Ltd
Imprint: CRC Press
Weight: 0.453kg
ISBN: 9781138374195
ISBN 10: 1138374199
Pages: 280
Publication Date: 14 November 2018
Audience:
College/higher education
,
General/trade
,
Tertiary & Higher Education
,
General
Format: Paperback
Publisher's Status: Active
Availability: In Print
This item will be ordered in for you from one of our suppliers. Upon receipt, we will promptly dispatch it out to you. For in store availability, please contact us.
Author Information
Raymond C. Valentine is Professor Emeritus at the University of California, Davis and Visiting Scholar in the Marine Science Institute at the University of California in Santa Barbara. David L. Valentine is an associate professor of earth science at the University of California in Santa Barbara.
