Overview

With the sequencing of several entire genomes, including that of Caenorrhabditis elegans, completed, the stage is set for the next phase of ""large-scale"" biology, the identification of the functionality of, and the interplay between, all genes and their protein products. The aim of the ESRF Workshop 29 and hence of this book was to review the models, the powerful methodology, and selected achievements of developmental biology, which has in the past two decades not only unveiled basic molecular mechanisms of ontogenesis, but also made important contributions to deciphering signal transduction pathways with general relevance to adult vertebrate physiology and ultimately to understanding mechanisms of pathogenesis.

Full Product Details

Author:   Christiane Nusslein-Volhard ,  Joern Kratzschmar
Publisher:   Springer-Verlag Berlin and Heidelberg GmbH & Co. KG
Imprint:   Springer-Verlag Berlin and Heidelberg GmbH & Co. K
Volume:   v. 29
ISBN:  

9783540663249

ISBN 10:   354066324
Pages:   260
Publication Date:   February 2000
Audience:   College/higher education ,  Professional and scholarly ,  Postgraduate, Research & Scholarly ,  Professional & Vocational
Format:   Hardback
Publisher's Status:   Active
Availability:   Awaiting stock  
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Table of Contents

Interactions Between Wingless and Frizzled Molecules in Drosophila.- Sequence Analysis of the C. elegans Genome and Proteome.- The Heterotrimeric G Protein Genes of Caenorhabditis elegans.- Programmed Cell Death and its Regulation of Initiation in C. elegans.- Presenilin Proteins and Their Function During Embryonic Development and Alzheimer's Disease.- Cell-Cell Interaction During Drosophila Embryogenesis.- Novel Mechanisms and Molecules.- The Roles of BMPs, BMP Antagonists, and the BMP Signaling Transducers SMAD1 and SMAD5 During Drosoventral Patterning of the Zebrafish Embryo.- Genetic Dissection of Heart Development.- Eph Receptors and Ephrins are Key Regulators of Morphogenesis.- Eph Receptor Tyrosine Kinases and Their Ligands in Development.- Embryonic Patterning of Xenopus Mesoderm by BMP-4.- The Indian Hedgehog - PTHrP System in Bone Development.- Hedgehog Signaling in Animal Development and Human Disease.

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