Overview

Nutrition in the Control of Inflammation: Emerging Roles for the Microbiome and Epigenome offers a comprehensive overview on how our diet promotes or attenuates inflammation to regulate inflammatory diseases. Broken into five sections, this book presents an introduction to the microbiome and epigenome in nutrition, subsequently covering diet, lifestyle, and the microbiome in the development of inflammatory diseases, nutrition and the epigenome in metabolic and cardiovascular diseases, diet, epigenetics, and microbiome. This book also addresses health-disparities in diet, epigenetics, and gut microbes. It will be of interest to nutrition researchers, nutritionists, and postgraduate students, as well as others working in, studying, and researching related fields.

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9780443189791

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Bradley S. Ferguson is an Associate Professor of Nutrition at the University of Nevada, Reno, Nevada. His lab adopts integrative, translational research approaches that encompass bioinformatics, in vitro cell culture, and in vivo animal models to elucidate dietary food components that act as epigenetic modifiers, as well as the role of dietary epigenetic modifiers on pathological cardiac signaling, gene expression, and remodeling. He also seeks to understand how sarcomere protein acetylation links metabolic disease (obesity and diabetes) to pathological cardiac remodeling and skeletal muscle dysfunction. Dr. Ferguson has published his findings across a wide range of peer-reviewed journals, including Scientific Reports, Journal of Animal Science, American Journal of Physiology, Cell Reports, PNAS, and the Journal of Molecular and Cellular Cardiology. Steven Frese is an Assistant Professor of Nutrition at the University of Nevada, Reno, Nevada and holds an appointment as an Adjunct Assistant Professor at the Department of Food Science and Technology at the University of Nebraska, Lincoln. His research applies principles of microbial ecology and evolutionary biology to develop rational interventions to improve human health via the gut microbiome. This includes applying advanced techniques including bioinformatics, DNA/RNA sequencing, and mass spectrometry to determine strain- and ecosystem-level interactions both in vitro and in human clinical trials. His work has primarily focused on the gut microbiome in early life, and the role of diet and the microbiome in shaping infant health and development. Dr. Frese’s work has been published in a variety of broad interest peer-reviewed journals including Cell, Science Translational Medicine, Cell Host & Microbe, and PLoS Genetics, as well as audience-specific journals including Pediatric Research, Glycobiology, and Bioinformatics.

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