Overview

Millions of patients experience persistent symptoms despite laboratory test results reported as ""normal."" Fatigue, brain fog, weight gain, anxiety, cold intolerance, palpitations, and mood changes are frequently dismissed when standard reference ranges appear acceptable. Normal Labs, Abnormal Life examines the limitations of population-based laboratory reference ranges in the evaluation of thyroid function. Drawing on clinical experience, this book explores how thyroid dysfunction-particularly autoimmune thyroid disease-may exist long before laboratory thresholds are crossed, and why biochemical ""normality"" does not always equate to physiological health. The book introduces the concept of impaired thyroid hormone availability and action at the tissue level, emphasizing mechanisms such as intracellular transport, hormone conversion, mitochondrial energy metabolism, and individual variability in hormone responsiveness. It discusses why symptom-based clinical patterns may precede abnormal laboratory findings by years and how reliance on isolated blood markers can delay meaningful diagnosis. Written for clinicians, healthcare professionals, and medically informed readers, Normal Labs, Abnormal Life encourages a more nuanced, physiology-driven interpretation of laboratory data and advocates for individualized clinical reasoning when standard results fail to explain patient experience.

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9786188815858

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Dr. Chilmi Ntalli, MD is a physician specializing in otorhinolaryngology (ENT) with extensive clinical experience in thyroid-related disorders and their systemic manifestations. His work focuses on the gap between laboratory reference ranges and real-world patient symptoms, with particular attention to functional physiology, intracellular thyroid hormone action, and diagnostic nuance.Through both clinical practice and writing, Dr. Ntalli aims to challenge reductionist interpretations of ""normal"" test results and advocate for more individualized, physiology-driven medical thinking.

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