Non-Obstructive Azoospermia: A Comprehensive Guide to Causes, Diagnosis, and Treatment

Author:   Wael Zohdy ,  Murat Gül ,  Rupin Shah ,  Ashok Agarwal
Publisher:   Springer International Publishing AG
ISBN:  

9783031994302


Pages:   350
Publication Date:   02 February 2026
Format:   Hardback
Availability:   Not yet available   Availability explained
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Non-Obstructive Azoospermia: A Comprehensive Guide to Causes, Diagnosis, and Treatment


Overview

Non-obstructive azoospermia (NOA) is characterized by the absence of sperm in the ejaculate due to a failure of the testes to produce sperm and is the cause of infertility in about 1% of adult men. This condition can result from various factors, including genetic abnormalities, hormonal imbalances, and environmental factors. Although NOA can make it difficult for men to conceive a child, there are treatment options available. These  include hormonal therapy, surgical procedures, and assisted reproductive techniques such as intracytoplasmic sperm injection (ICSI). The book begins with an introduction to NOA, including its definition, diagnosis, and epidemiology. The authors then provide a comprehensive discussion on the different aspects of NOA. Topics include  endocrine aberrations, the genetic spectrum of NOA, primary and secondary hypogonadism, fertility restoration, surgical approaches for sperm retrieval, and much more. It also explores the psychological and emotional impact of this condition on men and their partners. At the end, the book discusses the most recent international guidelines on NOA as well as what the future holds for NOA, such as experimental therapies, advancements in ART, and new research. Non-Obstructive Azoospermia: A Comprehensive Guide to Causes, Diagnosis, and Treatment provides a comprehensive understanding of NOA, including its causes, diagnosis, and treatment options. By sharing the latest research, clinical practices, and patient experiences, this book aims to provide a valuable resource for healthcare professionals, researchers, and patients dealing with non-obstructive azoospermia.

Full Product Details

Author:   Wael Zohdy ,  Murat Gül ,  Rupin Shah ,  Ashok Agarwal
Publisher:   Springer International Publishing AG
Imprint:   Springer International Publishing AG
ISBN:  

9783031994302


ISBN 10:   3031994302
Pages:   350
Publication Date:   02 February 2026
Audience:   Professional and scholarly ,  College/higher education ,  Professional & Vocational ,  Postgraduate, Research & Scholarly
Format:   Hardback
Publisher's Status:   Forthcoming
Availability:   Not yet available   Availability explained
This item is yet to be released. You can pre-order this item and we will dispatch it to you upon its release.

Table of Contents

Introduction to NOA.- Endocrine aberrations of NOA.- Genetic spectrum of NOA.- Differentiation between OA and NOA.- Imaging used in the evaluation of NOA.- Management of primary hypogonadism in men with NOA.- Management of secondary hypogonadism in men with NOA.- Follow-up and Monitoring of Adolescents with Delayed Puberty, Testicular Dysgenesis Syndrome.- Fertility restoration options for prepubertal boys undergoing gonadotoxic treatment.- The Role of Varicocele Repair in Patients with Nonobstructive Azoospermia.- Surgical approaches for sperm retrieval.- Predictors of Sperm Retrieval for Non-Obstructive Azoospermia.- Overview of the technical aspects in the lab.- Management of Non-Obstructive Azoospermia After Prior Failed Treatment.- Emotional and psychological impact of Non-Obstructive Azoospermia (NOA).- Summary of the Most Recent International Guidelines on Non-Obstructive Azoospermia.- Future of non-obstructive azoospermia (NOA).

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Author Information

Wael Zohdy Department of Andrology Cairo University Cairo, Egypt   Murat Gül Department of Urology Selcuk University School of Medicine Konya, Turkey   Rupin Shah Department of Urology Lilavati Hospital and Research Centre Mumbai, India   Ashok Agarwal Global Andrology Forum Moreland Hills, OH, United States Emeritus Staff, Cleveland Clinic Cleveland, OH, USA

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