Overview

In 2025, the Nobel Prize in Physiology or Medicine recognized a groundbreaking achievement that reshaped the future of immunology. Nobel Prize 2025 in Medicine explores how Mary Brunkow, Fred Ramsdell, and Shimon Sakaguchi uncovered the science behind immune tolerance, revealing how the human body prevents itself from turning against its own cells. Through clear storytelling and scientific insight, author Gary C. Mansfield takes readers inside the discovery of regulatory T cells (Tregs) and the FOXP3 gene-a revelation that changed our understanding of autoimmune diseases, immune regulation, and modern immunotherapy. Their research opened new doors for treating Type 1 diabetes, multiple sclerosis, lupus, and other disorders once thought incurable. Readers will discover how immune tolerance became a foundation for next-generation therapies, from cell-based treatments to gene editing and personalized medicine. This book is perfect for anyone interested in medical breakthroughs, Nobel Prize discoveries, or the quest to understand the body's most intelligent system-the immune system itself. Benefits for readers: Gain a clear understanding of how immune balance prevents disease. Learn the story behind the Nobel-winning discovery of Tregs and FOXP3. Understand the connection between genetics, immunology, and modern therapy. Explore how these discoveries influence today's biotechnology and medical research. A blend of science, history, and inspiration, Nobel Prize 2025 in Medicine shows that the greatest strength of the human body-and humanity itself-lies not in constant defense but in balance and tolerance.

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