Overview

This book presents the essential electrical events that shaped the creation of a planet that can support life, shaped membrane formation, single cell formation, single cell wound healing, multicellularity, epithelial tissues, basement membranes and many other biological events. This book aims to do three things: 1) enhance awareness of the lesser known contributions of electrical forces in life, 2) develop a picture of the all-embracing impact of electricity throughout biology and 3) as a consequence pave the way for new technologies that target these less well known electrical events. This book introduces a balanced and scientific thesis, that electrical forces are used ubiquitously throughout biology. It serves as a valuable resource for anyone interested in understanding the role of electricity in shaping life. The reader may also find how SARS-CoV-2 used electricity to infect humans and how we might tackle dementia.

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9783031688263

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Colin D. McCaig is a Fellow of the Royal Society of Edinburgh and was Regius Professor of Physiology, University of Aberdeen, for 20 years until retiring in 2022. His first paper, J.Physiol 314, 121-135 (1981), was seminal in reopening the issue of electrical guidance of nerve growth and wound healing. His lab and colleagues established that electrical signals control wound healing, nerve guidance and epithelial cell guidance in vivo and regulate proliferation and guidance of neurons, vascular endothelial cells, tumour cells and lens epithelial cells. Collectively these have major clinical relevance in tissue engineering and regenerative medicine. Several electrical devices to treat skin wounds are based on his wound healing studies.

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