Overview

Nitric Oxide Donors: Biomedical Applications and Perspectives presents the current state of art, challenges and innovations in the design of therapeutics nitric oxide donors with great impact in several aspects of human physiology and pathophysiology. Although considerable innovative progress has been achieved using Nitric Oxide donors in biomedical applications, certain drawbacks still need to be overcome to successfully translate these research innovations into clinical applications. This book encompasses several topics on nitric oxide such as its sources and biological properties; its performance in the cardiovascular and neurologic systems, in the human skin and its application in the treatment of neglected diseases, neurodegenerative disorders, and cancer. Additionally, it covers its role in inflammation and immunity, penile erection function, photodynamic therapy, antimicrobial activities. It also discusses the future of nitric oxide donors in combination with other therapeutic drugs, in implantable sensors, and nitric oxide releasing hydrogels and medical devices for topical applications. The book is a valuable source for researchers on different areas of biomedical field who are interested in the improvements that these molecules can make in the treatment of several conditions.

Full Product Details

Author:   Amedea Seabra (Associate Professor, Federal University of ABC (UFABC))
Publisher:   Elsevier Science Publishing Co Inc
Imprint:   Academic Press Inc
Weight:   0.770kg
ISBN:  

9780128092750

ISBN 10:   0128092750
Pages:   364
Publication Date:   23 March 2017
Audience:   Professional and scholarly ,  Professional & Vocational
Format:   Paperback
Publisher's Status:   Active
Availability:   Manufactured on demand  
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Table of Contents

1. Nitric Oxide Derivative Ruthenium Compounds as NO-Based Chemotherapeutic and Phototherapeutic Agents 2. Nitric Oxide Donors for Treating Neglected Diseases 3. Nitric Oxide-Donating Devices for Topical Applications 4. Nitric Oxide Donors and Therapeutic Applications in Cancer 5. Nitric Oxide Donors and Penile Erectile Function 6. Nitric Oxide Donors in Nerve Regeneration 7. Nitric Oxide Donors as Antimicrobial Agents 8. Improving the Performance of Implantable Sensors with Nitric Oxide Release 9. Strategies to Deliver Nitric Oxide Donors to Control Biofilms of Clinical and Industrial Interest 10. Developing New Organic Nitrates for Treating Hypertension 11. Nitric Oxide Donors in Brain Inflammation 12. Synergistic Activities of Nitric Oxide and Various Drugs 13. Hydrogels for Topical Nitric Oxide Delivery

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Author Information

Amedea B. Seabra holds a diploma degree in Chemistry from University of São Paulo (USP). She finished her Ph.D. at Chemistry Institute, State University of Campinas (UNICAMP) in 2006. Thereafter, she worked as a Research Fellow at UNICAMP (2006–2008), and she took postdoctoral studies at the Chemistry and Biochemistry Department, Concordia University in Montreal, Canada (2008–2010).She is associated professor at Federal University of ABC (UFABC). Her present research is focused on the preparation, characterization and evaluation of the cytotoxicity of nitric oxide-releasing nanomaterials for biomedical and agricultural applications.

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