Overview

Familiarity with nitric oxide is essential to a modern understanding of pathophysiologic mechanisms of infectious disease. Recent research has established nitric oxide and related reactive nitrogen intermediates to be important molecular mediators of diverse physiologic processes such as control of vascular tone, regulation of the immune system, and microbial and tumor cell growth. This book contains chapters by the leading researchers in the field and examines the biology and biochemistry of nitric oxide and its role in a variety of specific infections ranging from sepsis, tuberculosis and malaria to viral myocarditis, influenza, and AIDS.

Full Product Details

Author:   Ferric C. Fang
Publisher:   Springer-Verlag New York Inc.
Imprint:   Springer-Verlag New York Inc.
Edition:   Softcover reprint of the original 1st ed. 2002
Dimensions:   Width: 15.20cm , Height: 2.80cm , Length: 22.90cm
Weight:   0.788kg
ISBN:  

9781475786170

ISBN 10:   1475786174
Pages:   518
Publication Date:   26 March 2013
Audience:   Professional and scholarly ,  Professional & Vocational
Format:   Paperback
Publisher's Status:   Active
Availability:   Manufactured on demand  
We will order this item for you from a manufactured on demand supplier.

Table of Contents

An Overview of Nitric Oxide in Infection.- Historical Aspects of Nitric Oxide.- The Discovery of the Biological Synthesis of Nitric Oxide.- Biological Roles of Nitric Oxide.- Biochemistry of Nitric Oxide.- Enzymology of Nitric Oxide Biosynthesis.- Cytokine Regulation of Nitric Oxide Production.- Human Mononuclear Phagocyte Nitric Oxide Production and Inducible Nitric Oxide Synthase Expression.- Cardiovascular Actions of Nitric Oxide.- Biochemical Regulation of Nitric Oxide Cytotoxicity.- Cytoprotective Effects of NO against Oxidative Injury.- Immunomodulatory Actions of Nitric Oxide.- Nitric Oxide and Epithelial Host Defense.- Antimicrobial Properties of Nitric Oxide.- Nitric Oxide in Specific Infections.- Nitric Oxide in Sepsis.- Nitric Oxide in Mycobacterium tuberculosis Infection.- Nitric Oxide in Malaria.- Nitric Oxide in Schistosomiasis.- Nitric Oxide in Leishmaniasis.- Nitric Oxide in Viral Myocarditis.- Nitric Oxide in Influenza.- Nitric Oxide in Bacterial Meningitis.- Nitric Oxide in AIDS-Associated Neurological Disease.- Nitric Oxide in Listeriosis.- Future Directions.- Therapeutic Applications of Nitric Oxide in Infection.

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