Nitric Oxide and Cancer: Pathogenesis and Therapy

Author:   Benjamin Bonavida
Publisher:   Springer International Publishing AG
Edition:   Softcover reprint of the original 1st ed. 2015
ISBN:  

9783319352596


Pages:   308
Publication Date:   09 October 2016
Format:   Paperback
Availability:   Manufactured on demand   Availability explained
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Nitric Oxide and Cancer: Pathogenesis and Therapy


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Overview

Advances in Nitric Oxide and Cancer is a volume that serves to give the latest research on nitric oxide (NO) and cancer. More specifically, the volume reviews significant advances in the application of NO-mediated drugs. The volume explores nitric oxide and its relationship to cancer spanning from its roles in the pathogenesis, prognosis, gene and protein modifications, regulation of resistance to cytotoxics, and therapeutic applications. With chapters written by leading experts, the volume addresses the burgeoning interest in a rapidly advancing field and provides a valuable resource to scientists who have initiated research as well as clinical investigations in their laboratories on the various roles of NO and cancer.

Full Product Details

Author:   Benjamin Bonavida
Publisher:   Springer International Publishing AG
Imprint:   Springer International Publishing AG
Edition:   Softcover reprint of the original 1st ed. 2015
Dimensions:   Width: 15.50cm , Height: 1.80cm , Length: 23.50cm
Weight:   5.153kg
ISBN:  

9783319352596


ISBN 10:   3319352598
Pages:   308
Publication Date:   09 October 2016
Audience:   Professional and scholarly ,  Professional & Vocational
Format:   Paperback
Publisher's Status:   Active
Availability:   Manufactured on demand   Availability explained
We will order this item for you from a manufactured on demand supplier.

Table of Contents

Inflammation-associated Carcinogenesis Involved Interaction Between with iNOS/NO and WNT/beta-catenin.- NO and Genomic Stability.- Targeting Hyponitroxia in Cancer Therapy.- Mechanism of NO-dependent Regulation of Invasion and Metastasis.- NO Role in Protumorigenesis and Hypoxia.- Impacts of S-nitrosylation in Cancer.- S-nitrosylation of Cancer Cells.- Role of S-nitrosylation in Cancer Metastasis.- NO Immunity and Cancer.- Regulation of Anti-tumor Responses by NO.- NO Immune Modulation and Tumor Growth.- Role of NO in Chemo-immune Resistance.- Emerging Role of NO-mediated Therapeutics.- PDT and NO.- Regulation of Cell Death by NO.- Discovery and Development of RRx-001.- Nitric Oxide Coagulation and Cancer.- Neutrosphyngomyelinase 2.

Reviews

It describes the current perceptions on the role of NO. in cancer and a possible therapeutic application of NO. in the clinical practice. ... The book also presents several mechanisms of multiple effects and potential of NO. for therapeutic use under optimal conditions. It can be recommended to all readers who are interested in the pathogenesis and therapy of cancer. (Darina Slamenova, Neoplasma, Vol. 62 (6), 2015)


Author Information

Dr. Benjamin Bonavida is a professor at UCLA's David Geffen School of Medicine for the Department of Microbiology, Immunology, & Molecular Genetics. His other appointments include being a member of the Department of Defense Congressionally Directed Medical Research Program, Member of the National Cancer Institute's SPORE Program, member of the International Scientific Advisory Board of the Israel Cancer Research Foundation, to name a few. He's currently a scientific reviewer for several journals and a member of editorial boards including Journal of Clinical Immunology, International Journal of Oncology, and Cancer Biotherapy & Radiopharmaceuticals.

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