Overview

To give an update in the field of haemostasis, scientists and clinicians from overseas and European countries met to discuss the new trends in pathophysiology and clinical implications. This book is devoted to the interactions of endothelial functions, tissue factors, coagulation inhibitors and haemostasis as well as detection and prophylaxis of thromboembolism. Data of new research work on molecular and clinical approaches to diseases in haemostasis is presented. This book of proceedings on haemostasiology and angiology is intended for reseachers and clinicians.

Full Product Details

Author:   Job Harenberg ,  Dieter L. Heene ,  Gerd Stehle ,  Gotthard Schettler
Publisher:   Springer-Verlag Berlin and Heidelberg GmbH & Co. KG
Imprint:   Springer-Verlag Berlin and Heidelberg GmbH & Co. K
Edition:   Softcover reprint of the original 1st ed. 1990
Volume:   1990 / 1990/3
Dimensions:   Width: 17.00cm , Height: 1.50cm , Length: 24.20cm
Weight:   0.540kg
ISBN:  

9783540532750

ISBN 10:   3540532757
Pages:   270
Publication Date:   14 December 1990
Audience:   Professional and scholarly ,  Professional & Vocational
Format:   Paperback
Publisher's Status:   Active
Availability:   Out of stock  
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Table of Contents

Endothelial Functions and Haemostasis.- Structure, Shape and Function of Glycosaminoglycans.- Structure and Metabolism of Glycosaminoglycans.- Fibrin Polymerization and Its Role in Regulating Haemostasis.- Function of von Willebrand Factor in Plasma.- Biosynthesis and Assembly of the Factor VIII — von Willebrand Factor Complex.- Modulation of Endothelial Cell Function by Hypoxia: Perturbation of Barrier and Anticoagulant Function and Induction of a Novel Procoagulant Activity.- Tissue Factors and Endothelium.- Platelet Adhesion; A Concerted Action of Hemodynamic and Biochemical Processes.- Modulation of Endothelial Functions by Advanced Glycosylation End Products.- Procogulant Activities of Leukocytes.- Cytokine Induced Stimulation of Endothelial Cells in Vitro.- Anti-Platelet Treatment of Metastasis.- The Molecular Anatomy of Vitronectin as Extracellular Regulator Protein: Multifunctional Properties of the Heparin-Binding Domain.- Mode of Action of Annexin V (Vascular Anticoagulant Alpha), A Protein Synthesized by the Vessel Wall.- Coagulation Inhibitors and Haemostasis.- Clinical Pharmacologal Profile of Low Molecular Weight Heparins.- Anticoagulant Actions of Sulphated Polysaccharides.- Development of Synthetic Proteinase Inhibitors as Anticoagulant Agents.- Antithrombin and Its Deficiency States.- “New” Coagulation Inhibitors.- Biological Function of Vitamin K Antagonists.- Plasminogen Activator Inhibitors: Biological Effects.- Fibrin-Specific Clot Lysis with Single Chain Urokinase-Type Plasminogen Activator (scu-PA).- Antibody — Mediated Thrombolysis: Promise and Problems.- Thromboembolism: Detection and Prophylaxis.- Causation and Prevention of Coronary Thrombosis: Present Situation.- Non-Invasiva Diagnostic Techniques in Deep Vein Thrombosis.- Evaluationof the Bleeding Effects of Antithrombotic Drugs.- List of Participants.- List of Sponsors.

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