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Author:   Jacob E. Friedman (University of Colorado Health Sciences Center, Denver, CO, USA)
Publisher:   Elsevier Science & Technology
Imprint:   Elsevier Science Ltd
Volume:   v. 5
Dimensions:   Width: 16.50cm , Height: 1.80cm , Length: 24.00cm
Weight:   0.740kg
ISBN:  

9780444511584

ISBN 10:   044451158
Pages:   332
Publication Date:   10 August 2006
Audience:   Professional and scholarly ,  Professional & Vocational
Format:   Hardback
Publisher's Status:   Active
Availability:   Manufactured on demand  
We will order this item for you from a manufactured on demand supplier.

Table of Contents

1. PPARs as therapeutic targets for treating diabetes and insulin resistance 2. Genetic regulators of human obesity and diabetes 3. NF-kb, insulin resistance and the actions of salicylates 4. Wnt signaling and C/EBPs role in adipogenesis 5. Regulation of hepatic gluconeogenesis C/EPBs 6. Forkhead proteins and regulation of hepatic gene expression 7. Control of mitochondrial biogenesis through PGC-1 8. Regulation of PGC-1 in humans in insulin resistance and diabetes: Functional implications 9. FOXC2 controls resistance to obesity and Type II diabetes 10. SREB-1C regulation of nutrient homeostasis and lipid accumulation 11. GATA proteins as molecular gatekeeprs of the adipocyte 12. Diabetes regulation of gene expression by CREB 13. Molecular etiologies of MODY and other early-onset forms of diabetes 14. Liver X receptors as potential drug targets for Diabetes and its disorders 15. The potential therapeutic use of PPAR beta/delta agonists in lipid and glucose homeostasis 16. Influences of new PPAR insulin sensitizers on the metabolic syndrome in Rhesus Monkeys 17. PPARgamma and metabolism: Insights from the study of human genetic variants

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