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Author:   Leoncio Garrido (Consejo Superior de Investigaciones Cientifica, Spain) ,  Nicolau Beckmann (Novartis, Switzerland) ,  William Price ,  John Waterton
Publisher:   Royal Society of Chemistry
Imprint:   Royal Society of Chemistry
Volume:   Volume 2
Dimensions:   Width: 15.60cm , Height: 4.30cm , Length: 23.40cm
Weight:   1.022kg
ISBN:  

9781849734448

ISBN 10:   1849734445
Pages:   565
Publication Date:   24 July 2013
Audience:   Professional and scholarly ,  Professional and scholarly ,  Professional & Vocational ,  Professional & Vocational
Format:   Hardback
Publisher's Status:   Active
Availability:   In Print  
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Table of Contents

Introduction; Part I. Small Molecules, Proteins, Cellular Systems: New Applications of High Resolution NMR in Drug Discovery and Development; Solid-state NMR in Drug Discovery and Development; High-Resolution NMR-based Metabolic Profiling in Drug Discovery and Development; In-Cell NMR Spectroscopy to Study Protein–Drug Interactions; Part II. The Whole Organism In Vivo: Increased Sensitivity Using Cryogenic Radiofrequency Coils: Application to In Vivo Phenotyping of Mice; Recent Developments of Contrast Agents, CEST and Low Fields; Pharmacological fMRI in Drug Discovery and Development; In Vivo Proton MR Spectroscopy: Animal and Human Applications at High Fields; Hyperpolarization: Concepts, Techniques and Applications; Combined PET/MRI for Improving Quantitative Imaging; Magnetic Resonance-Based Cell Imaging Using Contrast Media and Reporter Genes; Part III. Translational drug discovery: From Biological Models to the Clinics; Translational Magnetic Resonance Imaging and Spectroscopy: Opportunities and Challenges; In Vivo MRI/S for the Safety Evaluation of Pharmaceuticals; Applications of MRI and MRS in Cartilage Therapeutics and Tissue Engineering; Applications of Magnetic Resonance Spectroscopy to Psychiatric Disorders; Structural Magnetic Resonance Imaging Biomarkers in Neurodegenerative Disease; Magnetic Resonance Imaging in Respiratory Diseases: From Diagnosis to Pharmaceutical Research and Development; Cardiovascular Magnetic Resonance; Magnetic Resonance Imaging Techniques in Cancer; Subject Index

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