Overview
Neuronal Nicotinic Receptors: Pharmacology and TherapeuticOpportunities Edited by Stephen P. Arneric and Jorge D. Brioni Nicotine's efficacy in the treatment of pain and anxiolysis, andits usefulness as a memory enhancer, have been suspected for manyyears, but research into the molecular biology of nicotinicacetylcholine receptors (nAChRs) traditionally has focused onsmoking cessation. Now, thanks to recent technological advances inthe molecular biology and electrophysiology of nAChRs, an abundanceof evidence has emerged in support of nAChR ligands in thetreatment of a range of CNS disorders, including Alzheimer'sdisease, Parkinson's disease, neuropathic pain, attention deficitdisorder, and depression. Featuring contributions from an international team of experts inthe field, this volume provides researchers and clinicians with acomprehensive review of nAChRs, their molecular biology,pharmacology, and clinical implications. Moving from the molecularto the clinical levels, the authors explore the latest developmentsin all areas of nAChR research, including: * Molecular biology and biochemistry of nAChRs * The physiological roles of nAChRs * Pharmacokinetics of nicotine-like alkaloids * Recent breakthroughs and emerging trends in nAChR medicinalchemistry * Current and emerging therapeutic applications of novel nAChRligands. A timely, authoritative review of basic research into nAChRs andtheir role in the development of new therapeutic strategies in thetreatment of a range of various CNS diseases, Neuronal NicotinicReceptors: Pharmacology and Therapeutic Opportunities is requiredreading for neuroscientists, pharmacologists, medicinal chemists,biological psychiatrists, and psychopharmacologists.
Full Product Details
Author: Stephen P. Arneric (DuPont/Merck, Wilmington, Delaware) ,
Jorge D. Brioni (Abbott Laboratories, Abbott Park, Illinois)
Publisher: John Wiley & Sons Inc
Imprint: Wiley-Liss Inc.,U.S.
Dimensions:
Width: 16.10cm
, Height: 2.80cm
, Length: 24.30cm
Weight: 0.771kg
ISBN: 9780471247432
ISBN 10: 047124743
Pages: 421
Publication Date: 02 February 1999
Audience:
College/higher education
,
Professional and scholarly
,
Undergraduate
,
Postgraduate, Research & Scholarly
Format: Hardback
Publisher's Status: Active
Availability: Out of stock
The supplier is temporarily out of stock of this item. It will be ordered for you on backorder and shipped when it becomes available.
Reviews
The book consists of a collection of 23 reviewers of 'things nicotonic' written by many...of the world's leaders in the field. Nearly without exception the chapters are chock full of valuable information. --Journal of Medicinal Chemistry, Vol. 42, No. 15, 1999
-The book consists of a collection of 23 reviewers of 'things nicotonic' written by many...of the world's leaders in the field. Nearly without exception the chapters are chock full of valuable information.- --Journal of Medicinal Chemistry, Vol. 42, No. 15, 1999
Author Information
Stephen P. Arneric and Jorge D. Brioni are the authors of Neuronal Nicotinic Receptors: Pharmacology and Therapeutic Opportunities, published by Wiley.
