Neuroblastoma: Molecular Mechanisms and Therapeutic Interventions

Author:   Swapan K. Ray (Professor, Department of Pathology, Microbiology, and Immunology, University of South Carolina School of Medicine, Columbia, South Carolina, USA)
Publisher:   Elsevier Science Publishing Co Inc
ISBN:  

9780128120057


Pages:   334
Publication Date:   17 January 2019
Format:   Paperback
Availability:   Manufactured on demand   Availability explained
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Neuroblastoma: Molecular Mechanisms and Therapeutic Interventions


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Author:   Swapan K. Ray (Professor, Department of Pathology, Microbiology, and Immunology, University of South Carolina School of Medicine, Columbia, South Carolina, USA)
Publisher:   Elsevier Science Publishing Co Inc
Imprint:   Academic Press Inc
Weight:   0.680kg
ISBN:  

9780128120057


ISBN 10:   0128120053
Pages:   334
Publication Date:   17 January 2019
Audience:   Professional and scholarly ,  College/higher education ,  Professional & Vocational ,  Postgraduate, Research & Scholarly
Format:   Paperback
Publisher's Status:   Active
Availability:   Manufactured on demand   Availability explained
We will order this item for you from a manufactured on demand supplier.

Table of Contents

1. Neuroblastoma pathology and classification 2. Role of genetic and epigenetic alterations in pathogenesis of neuroblastoma 3. Neuroblastoma molecular biology and promising therapeutic targets 4. The GD2-targeted immunotherapy of neuroblastoma 5. Targeting angiogenesis in neuroblastoma 6. Autophagy and novel therapeutic strategies in neuroblastoma 7. Energy metabolism and new therapeutic opportunities in neuroblastoma 8. Multimodality imaging for diagnosis of neuroblastoma 9. Immunotherapy for neuroblastoma 10. Advances in surgical treatment of neuroblastoma 11. Role of stemness factors in neuroblastoma: Neuroblastoma stem cells, tumor microenvironment, and chemoresistance 12. Current pharmacotherapy for neuroblastoma 13. Current challenges in the management of neuroblastoma 14. Novel therapeutic targets in neuroblastoma 15. Current and future strategies for treatment of relapsed neuroblastoma 16. Current evidence in favor of a tumor suppressor role of Krüppel-like factor 4 in malignant neuroblastoma 17. Modulation of expression of microRNA as a therapeutic strategy in malignant neuroblastoma

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Dr. Ray is senior faculty at the University of South Carolina School of Medicine with a deep interest in neuro-oncology. He has been working in the neuroblastoma field for more than 10 years has over 175 publications in the field and is funded by the federal, state, and private funding agencies for conducting his research. His laboratory focuses on the understanding of the cellular and molecular mechanisms of pathogenesis of malignant diseases such as glioblastoma, neuroblastoma, and Ewing's sarcoma and the development of novel therapeutic strategies for neurological disorders. He has trained many students, postdoctoral fellows, and junior faculty members as well.

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