Overview

This book is a comprehensive guide on neural stem cell behavior in health and disease. The book confers the altered behavior of endogenous neural stem cells in neurodegenerative disease conditions and the prospects of neural stem cell therapy for alleviating brain dysfunction in a variety of neurodegenerative disorders.Neural stem cell activity and neurogenesis in the adult brain is now confirmed in virtually all mammalian species including humans. Hence, a series of chapters in the first half of the book discusses the current knowledge on mechanisms of neural stem cell activity, the extent and functional significance of neurogenesis in the adult brain under normal, aged and disease environments, the susceptibility of neural stem cells and the plasticity of neurogenesis to alcohol, drugs of abuse and anesthetic agents, and advanced techniques that trigger neurogenesis in non-neurogenic regions.A second series of chapters in this book are focused on discussing the promise and efficacy of grafting of neural stem cells and/or other stem cells for treating neurological disorders such as Parkinson's disease, stroke, temporal lobe epilepsy, Alzheimer's disease and spinal cord injury. The final chapter confers on advances that are made in manufacturing a variety of neural cell types from human pluripotent stem cells that can be used as donor cells for cell transplantation.

Full Product Details

Author:   Ashok K Shetty (Texas A&m Health Science Center College Of Medicine, Usa)
Publisher:   World Scientific Publishing Co Pte Ltd
Imprint:   World Scientific Publishing Co Pte Ltd
Dimensions:   Width: 15.50cm , Height: 3.00cm , Length: 23.10cm
Weight:   1.043kg
ISBN:  

9789814623179

ISBN 10:   9814623172
Pages:   572
Publication Date:   16 October 2015
Audience:   College/higher education ,  Postgraduate, Research & Scholarly
Format:   Hardback
Publisher's Status:   Active
Availability:   In Print  
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Table of Contents

Neural Stem Cells - Introduction; Neural Stem Cell Functions in the Adult Hippocampus; Neural Stem Cell Behavior in the Subventricular Zone of the Forebrain; Neural Stem Cells and Age-Related Neurodegeneration; Neural Stem Cell Response to Traumatic Brain Injury; Neural Stem Cell Behavior and Neurogenesis in Epilepsy; Neural Stem Cell Dysfunction after Cancer Therapy; Neural Stem Cell Behavior in Alzheimer's Disease; Neural Stem Cells and Alcohol Use Disorders; Neural Stem Cell Behavior in Addiction; Vulnerability of Neural Stem Cells to Anaesthetic Agents; Induction of Neurogenesis from Astrocytes in Non-Neurogenic Regions of the Brain; Prospects of Neural Stem Cell Therapy for Alzheimer's Disease; Lab to Clinic Translation of Stem Cell Therapy for Stroke; Neural Stem Cell Therapy for Parkinson's Disease; Advances in Stem Cell Therapy for Temporal Lobe Epilepsy; Neural Stem Cell Therapy for Spinal Cord Injury; Generating the Right Neural Cell Types from Induced Pluripotent Stem Cells for Screening/Cell Therapy for CNS Disorders;

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