Overview

Neural Mechanisms of Addiction is the only book available that synthesizes the latest research in the field into a single, accessible resource covering all aspects of how addiction develops and persists in the brain. The book summarizes our most recent understanding on the neural mechanisms underlying addiction. It also examines numerous biobehavioral aspects of addiction disorders, such as reinforcement learning, reward, cognitive dysfunction, stress, and sleep and circadian rhythms that are not covered in any other publication. Readers with find the most up-to-date information on which to build a foundation for their future research in this expanding field. Combining chapters from leading researchers and thought leaders, this book is an indispensable guide for students and investigators engaged in addiction research.

Full Product Details

Author:   Mary Torregrossa, PhD (Assistant Professor, Department of Psychiatry, University of Pittsburgh, Pennsylvania, USA)
Publisher:   Elsevier Science Publishing Co Inc
Imprint:   Academic Press Inc
Weight:   1.000kg
ISBN:  

9780128122020

ISBN 10:   0128122021
Pages:   306
Publication Date:   29 August 2018
Audience:   Professional and scholarly ,  Professional & Vocational
Format:   Paperback
Publisher's Status:   Active
Availability:   Manufactured on demand  
We will order this item for you from a manufactured on demand supplier.

Table of Contents

1. Introduction Mary M. Torregrossa 2. Animal Models of Addiction Rita A. Fuchs 3. Transcriptional and Epigenetic Regulation of Reward Circuitry in Drug Addiction A.J. Robison 4. Neural Circuit Alterations in Addiction Matt Hearing and Eden Marie Anderson 5. Glutamatergic Neuroplasticity in Addiction L. A. Knackstedt and Allison Bechard 6. Neural Ensemble Encoding of Addictive Behavior Bruce Hope 7. Interoceptive Stimulus Effects of Drugs of Abuse Jennifer Murray 8. Maladaptive Memory Mechanisms in Addiction and Relapse Mary M. Torregrossa 9. Neural Morphology and Addiction Patrick Mulholland 10. Mechanisms regulating compulsive drug behaviors David M. Dietz 11. Role of Stress-Associated Signaling in Addiction John Mantsch and Elizabeth M. Doncheck 12. Negative Reinforcement Mechanisms in Addiction Olivier George 13. Circadian Rhythms and Addiction Ryan Logan 14. Role of Oxytocin in Countering Addiction-Associated Behaviors Exacerbated by Stress Jacqueline McGinty 15. The Role of Norepinephrine in Addiction: Past, Present, and Future David Weinshenker 16. Glial Dysregulation in Addiction David Baker 17. Role of the Extracellular Matrix in Addiction Peter W. Kalivas and Lauren Beloate 18. Striatal cell-type specific plasticity in addiction Mary Kay Lobo 19. Harnessing Circuits for the Treatment of Addictive Disorders Christelle Baunez 20. Conclusions and Future Directions Mary M. Torregrossa

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Author Information

Mary Torregrossa has conducted research in the neuroscience of addiction field for 16 years, including studying opiates, psychostimulants, alcohol, and cannabinoids in addition to investigating the neural mechanisms underlying addiction and potential treatments using a variety of techniques, including behavioral analyses, pharmacology, microdialysis, biochemistry, molecular biology, and proteomics. Dr. Torregrossa began her career by earning her Ph.D. at the University of Michigan in the laboratory of Dr. James Woods, one of the “founding fathers” of behavioral pharmacological studies of addictive disorders using animal models, and, as a postdoctoral fellow, trained with two other leaders in the addiction field, Dr. Peter Kalivas and Dr. Jane Taylor. Dr. Torregrossa is now an independent investigator in the Department of Psychiatry at the University of Pittsburgh, funded by the National Institute on Drug Abuse. She is the author of nearly 30 peer-reviewed articles in the field, as well as numerous reviews and book chapters.

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