Myeloproliferative Neoplasms: Critical Concepts and Management

Author:   Tiziano Barbui ,  Ayalew Tefferi
Publisher:   Springer-Verlag Berlin and Heidelberg GmbH & Co. KG
Edition:   2012
ISBN:  

9783642249884


Pages:   240
Publication Date:   03 February 2012
Format:   Hardback
Availability:   In Print   Availability explained
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Myeloproliferative Neoplasms: Critical Concepts and Management


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Overview

This book focuses on three of the main categories of myeloproliferative neoplasm: polycythemia vera, essential thrombocythemia, and primary myelofibrosis. Relevant laboratory and clinical advances are comprehensively covered, and great emphasis is placed on the practical issues that challenge physicians in their daily practice. The main topics considered thus include contemporary diagnostic  approaches, the value and limitations of mutation screening for diagnostic and  prognostic purposes, risk stratification in terms of both survival and other  disease complications such as leukemic transformation and thrombosis, and  modern therapeutic strategies, including conventional drugs, allogeneic stem cell  transplantation, and experimental drugs still under study. The reader will find Critical Concepts and Management Recommendations in Myeloproliferative Neoplasms to be an invaluable and up-to-date source of information from leading authorities in the field.

Full Product Details

Author:   Tiziano Barbui ,  Ayalew Tefferi
Publisher:   Springer-Verlag Berlin and Heidelberg GmbH & Co. KG
Imprint:   Springer-Verlag Berlin and Heidelberg GmbH & Co. K
Edition:   2012
Dimensions:   Width: 17.80cm , Height: 1.50cm , Length: 25.40cm
Weight:   0.702kg
ISBN:  

9783642249884


ISBN 10:   3642249884
Pages:   240
Publication Date:   03 February 2012
Audience:   Professional and scholarly ,  Professional & Vocational
Format:   Hardback
Publisher's Status:   Active
Availability:   In Print   Availability explained
This item will be ordered in for you from one of our suppliers. Upon receipt, we will promptly dispatch it out to you. For in store availability, please contact us.

Table of Contents

Biology.- Gerneral Issues in the Management of MPNs.- Specific Issues of Treatment in PV and ET.- Treatment of PMF.- Research Issues and Perspectives.

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The discovery of the JAK2 V617F mutation in the majority of patients with bcr/abl-negative myeloproliferative neoplasms has stimulated a number of questions regarding the diagnosis, prognosis, and treatment of polycythemia vera, essential thrombocythemia, and primary myelofibrosis. This book provides evidence-based reviews and expert consensus results concerning the key clinical issues for patient management. Practical recommendations are provided for the optimization and standardization of management of all three types of myeloproliferative neoplasm. Risk stratification, treatment goals, and first- and second-line therapies are discussed in detail, and other relevant diagnostic and research issues are also addressed. The reader will find Critical Concepts and Management Recommendations in Myeloproliferative Neoplasms to be an invaluable and up-to-date source of information from leading authorities in the field.

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