Overview

This detailed volume explores the application of multiplex biomarker methods in the critical area of COVID-19 research through state-of-the-art technologies in the fields of genomics, proteomics, transcriptomics, metabolomics, and imaging. The book features a series of protocols from labs across the globe employing multiplex molecular approaches, which can be applied to accelerate progress in the research of SARS-CoV-2 and other infectious illnesses. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.  Authoritative and essential, Multiplex Biomarker Techniques: Methods and Applications for COVID-19 Disease Diagnosis and Risk Stratification serves as a vital resource for researchers in the areas of virology, metabolic diseases, respiratory disorders, as well as to clinical scientists, physicians, pharmacologists, and the healthcare services.

Full Product Details

Author:   Paul C. Guest
Publisher:   Springer-Verlag New York Inc.
Imprint:   Springer-Verlag New York Inc.
Edition:   1st ed. 2022
Volume:   2511
Weight:   1.012kg
ISBN:  

9781071623947

ISBN 10:   107162394
Pages:   417
Publication Date:   16 July 2022
Audience:   Professional and scholarly ,  Professional & Vocational
Format:   Hardback
Publisher's Status:   Active
Availability:   Manufactured on demand  
We will order this item for you from a manufactured on demand supplier.

Table of Contents

Part I: Reviews   1. Multiplex Technologies in COVID-19 Research, Diagnostics, and Prognostics: Battling the Pandemic             Paul C. Guest, Fatemeh Zahedipour, Muhammed Majeed, Tannaz Jamialahmadi, and Amirhossein Sahebkar   2. Multivalent Vaccine Strategies in Battling the Emergence of COVID-19 Variants             Paul C. Guest   3. Challenges of Multiplex Assays for COVID-19 Research: A Machine Learning Perspective             Paul C. Guest, David Popovic, and Johann Steiner   Part II: Protocols   4. Multiplex Quantitative Polymerase Chain Reaction Diagnostic Test for SARS-CoV-2 and Influenza A/B Viruses             Steve F.C. Hawkins and Paul C. Guest   5. Multiplex Quantitative Polymerase Chain Reaction Test to Identify SARS-CoV-2 Variants             Steve F.C. Hawkins and Paul C. Guest   6. NIRVANA for Simultaneous Detection and Mutation Surveillance of SARS-CoV-2 and Co-Infections of Multiple Respiratory Viruses             Chongwei Bi, Gerardo Ramos-Mandujano, and Mo Li   7. Quantitative Real-Time RT-PCR Systems to Detect SARS-CoV-2             Sumino Yanase, Hiroyoshi Sasahara, Momoko Nabetani, Kensuke Yamazawa, Keisuke Aoyagi, Akiko Mita, Yuichi Honma, and Yasuhiko Chiba   8. Guidance for SARS-CoV-2 RNA-Based Molecular Assay Analytical Performance Evaluations             Lara Noble, Lesley Scott, Riffat Munir, Kim Steegen, Mignon du Plessis, Lucia Hans, and Wendy Stevens   9. A Rapid User-Friendly Lab-on-a-Chip Microarray Platform for Detection of SARS-CoV-2 Variants             Emily Mattig, Paul C. Guest, and Harald Peter   10. SARS-CoV-2 Host Immunogenetic Biomarkers             Maemu P. Gededzha, Nakampe Mampeule, Anastasia Gandini, and Elizabeth S. Mayne   11. FnCas9 Editor Linked Uniform Detection Assay for COVID-19             Rhythm Phutela, Sneha Gulati, Manoj Kumar, Souvik Maiti, and Debojyoti Chakraborty   12. Mass Spectrometry Multiplexed Detection of SARS-CoV-2             Luciana Godoy Viana, Adriana Lebkuchen, Rodrigo Andrade Schuch, Guilherme Gonçalves Okai, Jessica Silva Salgueiro, Karina Helena Morais Cardozo, and Valdemir Melechco Carvalho   13. Identification of Circulating Biomarkers of COVID-19 Using MALDI-TOF Mass Spectrometry             Lucas C. Lázari, Livia Rosa-Fernandes, and Giuseppe Palmisano   14. Antibody-Based Affinity Capture Combined with LC-MS Analysis for Identification of COVID-19 Disease Serum Biomarkers             Paul C. Guest and Hassan Rahmoune   15. Liquid Chromatography Mass Spectrometry Analysis of Peripheral Blood Mononuclear Cells from SARS-CoV-2 Infected Patients             Paul C. Guest and Hassan Rahmoune   16. Assay of Fatty Acids and Their Role in the Prevention and Treatment of COVID-19             Tharusha Jayasena, Sonia Bustamante, Anne Poljak, and Perminder Sachdev   17. Lab-on-a-Chip Immunoassay for Prediction of Severe COVID-19 Disease             Harald Peter, Emily Mattig, Paul C. Guest, and Frank F. Bier   18. Multiplex Immunoassay for Prediction of Disease Severity Associated with the Cytokine Storm in COVID-19 Cases             Paul C. Guest, Mitra Abbasifard, Tannaz Jamialahmadi, Muhammed Majeed, Prashant Kesharwani, and Amirhossein Sahebkar   19. Detection of IgG Antibodies to SARS-CoV-2 and Neutralizing Capabilities Using the Luminex® xMAP® SARS-CoV-2 Multi-Antigen IgG Assay             Abbe King, Gregory King, Christy Weiss, Sherry Dunbar, and Shubhagata Das   20. Multiplex Testing of the Effect of Statins on Disease Severity Risk in COVID-19 Cases             Fatemeh Zahedipour, Paul C. Guest, Muhammed Majeed, Khalid Al-Rasadi, Tannaz Jamialahmadi, and Amirhossein Sahebkar   21. Evaluating the Effects of Curcumin on the Cytokine Storm in COVID-19 Using a Chip-Based Multiplex Analysis             Fatemeh Zahedipour, Paul C. Guest, Muhammed Majeed, Prashant Kesharwani, Tannaz Jamialahmadi, and Amirhossein Sahebkar   22. COVID-19 Detection Using the NHS Lateral Flow Test Kit             Paul C. Guest and Hassan Rahmoune   23. Evaluation Protocol for SARS-CoV-2 Serological Assays             Maemu P. Gededzha, Sarika Jugwanth, Nakampe Mampeule, Nontobeko Zwane, Anura David, Lesley Scott, Wendy Stevens, and Elizabeth S. Mayne   24. Measurement of Mitochondrial Respiration in Cryopreserved Human Peripheral Blood Mononuclear Cells (PBMCs)             Keiko Iwata, Min-Jue Xie, Paul C. Guest, Takaharu Hirai, and Hideo Matsuzazki   25. Multiplex Testing of Oxidative-Reductive Pathway in Patients with COVID-19 Disease             Paul C. Guest, Mitra Abbasifard, Tannaz Jamialahmadi, Muhammed Majeed, Prashant Kesharwani, and Amirhossein Sahebkar   26. Point-of-Care Device for Assessment of Blood Coagulation Status in COVID-19 Patients             Paul C. Guest and Hassan Rahmoune   27. COVID-19 and the Assessment of Coenzyme Q10             Nadia Turton, Robert A. Heaton, and Iain P. Hargreaves   28. Isolation and Cell Culture of Human Nasopharyngeal Cells: A Model for Testing Immune Response and Antiviral Treatment             Krist Helen Antunes and Ana Paula Duarte de Souza   29. Machine Learning Approaches to Analyze MALDI-TOF Mass Spectrometry Protein Profiles             Lucas C. Lázari, Livia Rosa-Fernandes, and Giuseppe Palmisano   30. A Deep Learning Approach to Identify Chest Computed Tomography Features for Prediction of SARS-CoV-2 Infection Outcomes             Amirhossein Sahebkar, Mitra Abbasifard, Samira Chaibakhsh, Paul C. Guest, Mohamad Amin Pourhoseingholi, Amir Vahedian-Azimi, Prashant Kesharwani, and Tannaz Jamialahmadi   Part III: Future Perspectives   31. Genomic Surveillance for Monitoring Variants of Concern: SARS-CoV-2 Delta, Omicron, and Beyond             Paul C. Guest

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