Multiple Origins of Sex Differences in Brain: Neuroendocrine Functions and Their Pathologies

Author:   Dr Donald W Pfaff, PhD (Rockefeller University, New York) ,  Vice-President Yves Christen (Foundation Ipsen, Paris)
Publisher:   Springer
ISBN:  

9781299335530


Pages:   187
Publication Date:   01 January 2013
Format:   Electronic book text
Availability:   Available To Order   Availability explained
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Multiple Origins of Sex Differences in Brain: Neuroendocrine Functions and Their Pathologies


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Overview

In theoretical terms, sex differences in brains and behaviors of laboratory animals offer the possibility of fascinating scientific studies on a range of molecular phenomena such as genomic imprinting, DNA methylation, chromatin protein modification, non-coding DNA, potentially resulting in important neuroanatomical and neurochemical sex differences in the brain. Such sex differences could arise consequent to exposures to testosterone early in development, or to other effects deriving from the Y chromosome. However, this general subject has been treated with much hyperbole. Historically, sex differences were assumed to be present where they did not really exist, e.g. with respect to mathematics, executive leadership, etc. etc. Under what circumstances do we really care about sex differences in brain and behavior? These circumstances concern human maladies whose diagnoses are much different between boys and girls, or between women and men. Prominent examples discussed in this volume include autism, attention deficit hyperactivity disorders and congenital adrenal hyperplasia. In fact, infant boys are more susceptible than infant girls to a variety of disorders that arise early in development. This volume then ends with a consideration of effects of estrogenic hormones on the injured brain, and their roles as protective agents.

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Author:   Dr Donald W Pfaff, PhD (Rockefeller University, New York) ,  Vice-President Yves Christen (Foundation Ipsen, Paris)
Publisher:   Springer
Imprint:   Springer
ISBN:  

9781299335530


ISBN 10:   1299335535
Pages:   187
Publication Date:   01 January 2013
Audience:   General/trade ,  General
Format:   Electronic book text
Publisher's Status:   Active
Availability:   Available To Order   Availability explained
We have confirmation that this item is in stock with the supplier. It will be ordered in for you and dispatched immediately.

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