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Author:   Manfred Clynes
Publisher:   Kluwer Academic Publishers
Imprint:   Kluwer Academic Publishers
Weight:   1.156kg
ISBN:  

9780792326694

ISBN 10:   0792326695
Pages:   400
Publication Date:   28 February 1994
Audience:   College/higher education ,  Professional and scholarly ,  Undergraduate ,  Postgraduate, Research & Scholarly
Format:   Hardback
Publisher's Status:   Active
Availability:   Out of stock  
The supplier is temporarily out of stock of this item. It will be ordered for you on backorder and shipped when it becomes available.

Table of Contents

P-glycoprotein structure and evolutionary homologies; J.M. Croop. Molecular analysis of the multidrug transporter; U.A. Germann. Molecular cytogenetics of multiple drug resistance; P.V. Schoenlein. Antibodies in the study of multiple drug resistance; Y. Heike, T. Tsuruo. Non-glycoprotein multidrug resistance in cell lines which are defective in the cellular accumulation of drug; M.S. Center. Topoisomerase I in multiple drug resistance; A. Pessina. Topoisomerase II in multiple drug resistance; G.A. Hoffmann, M.R. Mattern. Glutathione-related enzymes, glutathione and multidrug resistance; J.A. Moscow, K.H. Dixon. Pharmacologic circumvention of multidrug resistance; J.M. Ford, W.N. Hait. Multidrug resistance (MDR) genes in haematological malignancies; K. Nooter, P. Sonneveld. Human cell lines as models for multidrug resistance in solid tumours; M. Clynes, M. Heenan, K. Hall. Studies on low-level MDR cells; G. Belvedere, E. Dolfini. Differing patterns of cross-resistance resulting from exposures to specific antitumour drugs or to radiation; B.T. Hill. The use of reverse transcriptase-polymerase chain reaction (RT-PCR) to investigate specific gene expression in multidrug-resistant cells; L. O'Driscoll, C. Daly, M. Saleh, M. Clynes. Mathematical models for multidrug resistance and its reversal; S. Michelson. The biology of radioresistance: similarities, differences and interactions with drug resistance; S.N. Powell, Abraham. Kinetic resistance to anticancer agents; M.-T. Dimanche-Boitrel, C. Garrido, B. Chauffert. Cytochromes P450 and drug resistance; J. Doehmer, A.R. Goeptar, N.P.E. Vermeulen. Role of matrix metalloproteinases in invasion and metastasis: biology, diagnosis and inhibitors; S. McDonnell, B. Fingleton. Clinical significance of cellular resistance in tumours to cytotoxic chemotherapy and radiotherapy; M. Pomeroy, A.P. Moriarty.

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