Overview

This book brings together the latest knowledge on moyamoya disease, covering diagnostic criteria, status as a disease entity, genetic aspects, pathophysiology, novel neuroradiological findings, and surgical therapy. Information is also provided on recent basic and clinical research with the aim of identifying future perspectives on the disease. Since moyamoya disease was first reported in an English language article more than 50 years ago, our understanding of it has advanced considerably. Genetic and radiological analysis has delivered novel insights, and the latest multicenter studies are changing routine diagnosis and surgical therapy. The gene encoding the ring finger protein 213 (RNF213) has been identified as a susceptibility gene for moyamoya disease. Indications and procedures for surgical revascularization have been revised, with resultant improvements in outcomes, and studies performed over the past decade have provided new knowledge on the neuroradiological findings before and after surgery. In describing these advances, this book will be an invaluable asset for all general physicians, pediatricians, neurologists, radiologists, and neurosurgeons who care for patients with moyamoya disease across the world.

Full Product Details

Author:   Satoshi Kuroda
Publisher:   Springer Verlag, Singapore
Imprint:   Springer Verlag, Singapore
Edition:   1st ed. 2021
Weight:   0.790kg
ISBN:  

9789813364035

ISBN 10:   9813364033
Pages:   341
Publication Date:   27 February 2021
Audience:   Professional and scholarly ,  Professional & Vocational
Format:   Hardback
Publisher's Status:   Active
Availability:   Manufactured on demand  
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Table of Contents

Part I Concept of Moyamoya Disease.- 1 History of Disease Entity & Diagnosis Criteria.- 2 Moyamoya Syndrome.- 3 Unilateral Moyamoya Disease: A Distinct Entity?.- Part II Genetic Aspect of Moyamoya Disease.- 4 RNF213 as Susceptibility Gene.- 5 RNF213 and clinical feature.- 6 RNF213 Variant as a Biomarker of Cerebrovascular Disease.- Part III Pathophysiology of Moyamoya Disease.- 7 TIA & Headache in Pediatric Moyamoya Disease.- 8 Ischemic stroke.- 9 Hemorrhagic Stroke and the Japan Adult Moyamoya Trial.- 10 Cognitive Function in Pediatric Moyamoya Disease.- 11 Cognitive Dysfunction in Adults.- 12 Asymptomatic Moyamoya Disease.- Part IV Update on Neuroradiology in Moyamoya Disease.- 13 Periventricular Anastomosis.- 14 Arterial Shrinkage.- 15 Disease progression.- 16 Postoperative hyperperfusion.- 17 Postoperative FLAIR Imaging Changes.- Part V Real World of Surgical Revascularization for Moyamoya Disease.- 18 Overview of Surgical Revascularization and Long-term Outcome in Japan.- 19 Perioperative complications.- 20 Long-term Outcome in Europe.- 21 Long Term Outcomes in USA.- 22 Long-term Outcome in China.- 23 Long-term outcome of revascularization surgery for moyamoya disease in Korea.- 24 Indirect bypass surgery for moyamoya disease.- 25 Direct/combined bypass surgery.- 26 Special Considerations—Infants.- 27 Special Considerations – Elderly.

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Author Information

Professor Satoshi Kuroda, MD, PhD, IFAANS Department of Neurosurgery, Graduate School of Medicine and Pharmaceutical Science, University of Toyama, Toyama, Japan skuroda@med.u-toyama.ac.jp

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