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Author:   Gabriele Proetzel ,  Michael V. Wiles
Publisher:   Humana Press Inc.
Imprint:   Humana Press Inc.
Edition:   2nd ed. 2016
Volume:   1438
Dimensions:   Width: 17.80cm , Height: 2.50cm , Length: 25.40cm
Weight:   9.806kg
ISBN:  

9781493936595

ISBN 10:   149393659
Pages:   436
Publication Date:   06 May 2016
Audience:   Professional and scholarly ,  Professional & Vocational
Format:   Hardback
Publisher's Status:   Active
Availability:   Manufactured on demand  
We will order this item for you from a manufactured on demand supplier.

Table of Contents

Genetically Defined Strains in Drug Development and Toxicity Testing.- Simple, Efficient CRISPR-Cas9 Mediated Gene Editing in Mice: Strategies and Methods.- Mouse Sperm Cryopreservation and Recovery of Genetically Modified Mice.- Generation of Immunodeficient Mice Bearing Human Immune Systems by the Engraftment of Hematopoietic Stem Cells.- Generation of Human Liver Chimeric Mice for the Study of Human Hepatotropic Pathogens.- Human FcRn Transgenic Mice for Pharmacokinetic Evaluation of Therapeutic Antibodies.- A Humanized Mouse Model to Study Human Albumin and Albumin Conjugates Pharmacokinetics.- Germ-Free Mice Model for Studying Host-Microbial Interactions.- Bridging Mice to Men: Using HLA Transgenic Mice to Enhance the Future Prediction and Prevention of Autoimmune Type 1 Diabetes in Humans.- Mouse Models of Type 2 Diabetes Mellitus in Drug Discovery.- Cholesterol Absorption and Metabolism.- Skin Diseases in Laboratory Mice: Approaches to Drug Target Identification and Efficacy Screening.- Chronic Myeloid Leukemia (CML) Mouse Model in Translational Research.- Murine Model for Colitis-Associated Cancer of the Colon.- Mouse Models for Studying Depression-Like States and Antidepressant Drugs.- Experimental Models of Anxiety for Drug Discovery and Brain Research.- Repetitive Behavioral Assessments for Compound Screening in Mouse Models of Autism Spectrum Disorders.- Better Utilization of Mouse Models of Neurodegenerative Diseases in Preclinical Studies: From the Bench to the Clinic.- Neuromuscular Disease Models and Analysis.- Brightfield Imaging and Optical Coherence Tomography of the Mouse Posterior Eye.- Mouse Models as Tools to Identify Genetic Pathways for Retinal Degeneration, as Exemplified by Leber's Congenital Amaurosis.

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