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OverviewCongenital malformations are worldwide occurrences striking in every condition of society. These severe physical abnormalities which are present at birth and affecting every part of the body happen more often than usually realized, once in every 33 births. The most common, after heart defects, are those of the neural tube (the brain and spinal cord) which happen in as many as one in every 350 births. They have been noted as curiousities in man and beast throughout recorded history and received great attention in our time by various fields of study, for example, their faulty prenatal development by embryologists, familial patterns by geneticists, causation by environmentalists and variability by population scientists. Attention turned much in recent years to the relation of these malformations to deficiency of a particular dietary ingredient, folic acid, a subject this book analyzes in depth. The greatest conundrum of all, which this latest matter like so much else hinges on, is the amazing fact of the tremendous, almost universal decrease in the frequency of these anomalies since early in the 20th century. The puzzle is ‘What can this downward trend possibly mean?’ and at bottom ‘Whether it is part of a long-term cyclical pattern’. This fascinating biological phenomenon is explored in the book together with various other topics. Full Product DetailsAuthor: Harold KalterPublisher: Springer-Verlag New York Inc. Imprint: Springer-Verlag New York Inc. Edition: 2009 Dimensions: Width: 15.50cm , Height: 1.70cm , Length: 23.50cm Weight: 1.260kg ISBN: 9781402096051ISBN 10: 1402096054 Pages: 265 Publication Date: 27 February 2009 Audience: Professional and scholarly , Professional & Vocational Format: Hardback Publisher's Status: Active Availability: In Print ![]() This item will be ordered in for you from one of our suppliers. Upon receipt, we will promptly dispatch it out to you. For in store availability, please contact us. Table of ContentsIntroduction: Basic Stuff.- Neural Tube Defects.- Setting the Stage.- Studies in the Old World.- The Continent of Europe.- The United States.- Geography and Chronology.- Canada.- Australia and New Zealand.- Blacks and Jews.- The Mideast.- Asia.- The Sex Ratio Phenomenon.- Abortion.- Fetal Diagnosis of Neural Tube Defect.- Etiology I: Early Questions.- Etiology II.- Neural Tube Defects in China.- The Ultimate Question.- The Future.ReviewsAuthor InformationTab Content 6Author Website:Countries AvailableAll regions |