Molecular Structures and Structural Dynamics of Prion Proteins and Prions: Mechanism Underlying the Resistance to Prion Diseases

Author:   Jiapu Zhang
Publisher:   Springer
Edition:   Softcover reprint of the original 1st ed. 2015
Volume:   9
ISBN:  

9789402404456


Pages:   355
Publication Date:   29 October 2016
Format:   Paperback
Availability:   Manufactured on demand   Availability explained
We will order this item for you from a manufactured on demand supplier.

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Molecular Structures and Structural Dynamics of Prion Proteins and Prions: Mechanism Underlying the Resistance to Prion Diseases


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Author:   Jiapu Zhang
Publisher:   Springer
Imprint:   Springer
Edition:   Softcover reprint of the original 1st ed. 2015
Volume:   9
Weight:   6.363kg
ISBN:  

9789402404456


ISBN 10:   9402404457
Pages:   355
Publication Date:   29 October 2016
Audience:   Professional and scholarly ,  Professional & Vocational
Format:   Paperback
Publisher's Status:   Active
Availability:   Manufactured on demand   Availability explained
We will order this item for you from a manufactured on demand supplier.

Table of Contents

Basic Knowledge.- The Homology Structure and Dynamics.- The NMR Structure and Dynamics of the Wild-type and Mutants.- Compared with the NMR Structure and Dynamics of Humans and Mice.- Compared with the NMR Structure and Dynamics of Dogs and Horses.- Compared with a Homology Structure and Dynamics of Buffaloes.- Compared with NMR Structure and Dynamics of Elks.- Compared with the X-ray Structure and Dynamics of Rabbits.- Surface Electrostatic Charge Distributions.- The Hydrophobic Region PrP(109–136).- The Hybrid Method of Steepest Descent - Conjugate Gradient with Simulated Annealing.- Hybrid Method of Discrete Gradient with Simulated Annealing or Genetic Algorithm.- A Novel Canonical Dual Global Optimization Computational Approach.- The Hybrid Method of Evolutionary Computations with Simulated Annealing.- Simulated Annealing Refined Replica Exchange Global Search Algorithm.- LBFGS Quasi-Newtonian Methods for MM Prion AGAAAAGA Amyloid Fibrils.- Particle Swarm Global Optimization Search Algorithm.- A Summary of the Research Works on AGAAAAGA.

Reviews

There is a wealth of information and insight in the results presented and in the methods employed. The research is important. The methods used are innovative. Studying this book is worth the effort. (Anthony J. Duben, Computing Reviews, computingreviews.com, September, 2016)


“There is a wealth of information and insight in the results presented and in the methods employed. The research is important. The methods used are innovative. Studying this book is worth the effort.” (Anthony J. Duben, Computing Reviews, computingreviews.com, September, 2016)


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