Molecular Pathogenesis and Treatment of Chronic Myelogenous Leukemia

Author:   Masahiro Kizaki
Publisher:   Springer Verlag, Japan
Edition:   1st ed. 2016
ISBN:  

9784431557135


Pages:   193
Publication Date:   13 November 2015
Format:   Hardback
Availability:   Manufactured on demand   Availability explained
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Molecular Pathogenesis and Treatment of Chronic Myelogenous Leukemia


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Author:   Masahiro Kizaki
Publisher:   Springer Verlag, Japan
Imprint:   Springer Verlag, Japan
Edition:   1st ed. 2016
Dimensions:   Width: 15.50cm , Height: 1.70cm , Length: 23.50cm
Weight:   4.691kg
ISBN:  

9784431557135


ISBN 10:   443155713
Pages:   193
Publication Date:   13 November 2015
Audience:   Professional and scholarly ,  Professional & Vocational
Format:   Hardback
Publisher's Status:   Active
Availability:   Manufactured on demand   Availability explained
We will order this item for you from a manufactured on demand supplier.

Table of Contents

1. Identification and Biology of CML Stem Cells.- 2. Molecular Mechanisms of CML Stem Cell Maintenance.- 3. Roles for Signaling Molecules in the Growth and Survival of CML Cells.- 4. Goal of CML Treatment in the Tyrosine Kinase Inhibitor Era.- 5. Biomarkers for Determining the Prognosis of CML.- 6. Updated European Leukemia Net Recommendations for the Management of CML.- 7. Optimal Monitoring of CML Treatment: Molecular and Mutation Analysis.- 8. Recommendations for Management of CML in the Era of Second-Generation TKIs.- 9. Role of New TKIs and Combinations with Interferon-α for the Treatment of CML.- 10. Safety Profiles of First-Line TKIs and Managing Adverse Effects.- 11. Molecular Mechanism of TKI Resistance and Potential Approaches to Overcome Resistance.- 12. Discontinuation of Therapy and Treatment-Free Remission in CML.

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Professor and Chairman of Department of Hematology in Saitama Medical Center, Saitama Medical University.

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