Overview

This volume reviews the current state of research concerning bacterial virulence factors and the infection biology of Helicobacter pylori, which is the leading cause of peptic ulcers and gastric cancer worldwide. The chapters include cutting-edge findings on this fascinating microbe and discuss the general strategies of H. pylori infection and persistence, news on important H. pylori virulence factors, crosstalk with the microbiota, hot novel models and signaling mechanisms, risk factors of gastric disease and stomach cancer, and the impact of H. pylori infection on non-gastric diseases. Written by internationally respected scientists, this book will appeal to clinicians, researchers and advanced students alike.

Full Product Details

Author:   Nicole Tegtmeyer ,  Steffen Backert
Publisher:   Springer International Publishing AG
Imprint:   Springer International Publishing AG
Edition:   Softcover reprint of the original 1st ed. 2017
Volume:   400
Dimensions:   Width: 15.50cm , Height: 2.00cm , Length: 23.50cm
Weight:   0.575kg
ISBN:  

9783319844183

ISBN 10:   3319844180
Pages:   347
Publication Date:   13 July 2018
Audience:   Professional and scholarly ,  Professional & Vocational
Format:   Paperback
Publisher's Status:   Active
Availability:   Manufactured on demand  
We will order this item for you from a manufactured on demand supplier.

Table of Contents

The human stomach in health and disease: infection strategies by Helicobacter pylori.- Human and Helicobacter pylori Interactions Determine the Outcome of Gastric Diseases.- Immune evasion strategies and persistence of Helicobacter pylori.- Recent advances in Helicobacter pylori replication: possible implications in adaptation to a pathogenic lifestyle and perspectives for drug design.- The Helicobacter pylori Methylome: Roles in Gene Regulation and Virulence.- Structural insights into Helicobacter pylori Cag protein interactions with host cell factors.- Gastric organoids: An emerging model system to study Helicobacter pylori pathogenesis.- DNA Transfer and Toll-Like Receptor Modulation by Helicobacter pylori.- Exploiting the gastric epithelial barrier: Helicobacter pylori’s attack on tight and adherens junctions.- Helicobacter pylori-induced Changes in Gastric Acid Secretion and Upper Gastrointestinal Disease.- Impact of the microbiota and gastric disease development by Helicobacter pylori.- Pathogenesis of gastric cancer: genetics and molecular classification.- Helicobacter pylori-mediated genetic instability and gastric carcinogenesis.- Helicobacter pylori and extragastric diseases.

Reviews

Author Information

Dr. rer. nat. Nicole Tegtmeyer Prof. Dr. rer. nat. Steffen Backert Chair of Microbiology Friedrich Alexander University Erlangen/Nuremberg Department of Biology, Division of Microbiology Staudtstr. 5 91058 Erlangen Germany

Tab Content 6

Author Website:  

Customer Reviews

Recent Reviews

No review item found!

Add your own review!

Countries Available

All regions