Overview

In this issue of Clinics in Laboratory Medicine, guest editor Dr. Fei Dong brings his considerable expertise to the topic of Molecular Oncology Diagnostics. Top experts in the field review current practices in molecular oncology diagnostics, highlighting the rapid clinical adoption of next generation sequencing techniques. The articles address key laboratory considerations in the molecular testing of cancer specimens and the impact of advanced testing strategies on patient care. Contains 15 practice-oriented topics including utility of single gene testing in cancer specimens; analytical principles of cancer next generation sequencing; principles and validation of bioinformatics pipelines for cancer next generation sequencing; panel sequencing for targeted therapy selection in solid tumors; and more.  Provides in-depth clinical reviews on molecular oncology diagnostics, offering actionable insights for clinical practice.  Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create clinically significant, topic-based reviews. 

Full Product Details

Author:   Fei Dong, MD (Associate Pathologist , Brigham and Women's Hospital , Assistant Professor , Harvard Medical School)
Publisher:   Elsevier - Health Sciences Division
Imprint:   Elsevier - Health Sciences Division
Weight:   4.120kg
ISBN:  

9780323849364

ISBN 10:   0323849369
Pages:   240
Publication Date:   23 September 2022
Audience:   Professional and scholarly ,  Professional & Vocational
Format:   Hardback
Publisher's Status:   Active
Availability:   Manufactured on demand  
We will order this item for you from a manufactured on demand supplier.

Table of Contents

Panel Sequencing for Targeted Therapy Selection in Solid Tumors Molecular Diagnostic Testing for Hematopoietic Neoplasms: Linking Pathogenic Drivers to Personalized Diagnosis Special Considerations in the Molecular Diagnostics of Pediatric Neoplasms Specimen Considerations in Molecular Oncology Testing Utility of Single-Gene Testing in Cancer Specimens Analytical Principles of Cancer Next Generation Sequencing Principles and Validation of Bioinformatics Pipeline for Cancer Next-Generation Sequencing Best Practice for Clinical Somatic Variant Interpretation and Reporting Molecular Detection of Oncogenic Gene Rearrangements Copy Number Analysis in Cancer Diagnostic Testing Molecular Biomarkers of Response to Cancer Immunotherapy When Tissue Is the Issue: Expanding Cell-Free DNA Liquid Biopsies to Supernatants and Nonplasma Biofluids Germline Testing for the Evaluation of Hereditary Cancer Predisposition

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