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OverviewThe book is a collection of up-to-date reviews by major researchers in the field of the fast-moving area of modern immunology. Its wide scope, depth of coverage, well-illustrated text, and the eminence of the authorship make it unique in its field. Over 1900 literature reference are cited. So much has happened in immunology since publication of the first edition of this popular book seven years ago that the second edition is a major new work. The chapters on mechanism and control of immunoglobulin genes by Fred Alt and his colleagues, T-cell antigen receptor genes by Mark Davis and Yeuh-hsui Chien, T lymphocyte signal transduction by Cox Terhorst et al, and the complement system by Ken Reid are all major updates and extensions of their first edition contributions. In addition, the second edition contains new chapters by David Jewell and Ian Wilson on the structure and function on MHC class I and class II antigens, by John Monaco on molecular mechanisms of antigen processing. By Gerry Klaus on B cell activation, and by Martine Verhoeyen and John Windust in recent advances by antibody engineering. Full Product DetailsAuthor: B. D. Hames (Department of Biochemistry and Molecular Biology, Department of Biochemistry and Molecular Biology, University of Leeds) , D. M. Glover (Department of Anatomy and Physiology, Department of Anatomy and Physiology, University of Dundee)Publisher: Oxford University Press Imprint: Oxford University Press Edition: 2nd Revised edition Volume: 11 Dimensions: Width: 18.90cm , Height: 2.20cm , Length: 24.60cm Weight: 0.787kg ISBN: 9780199633784ISBN 10: 0199633789 Pages: 404 Publication Date: 08 February 1996 Audience: Professional and scholarly , Professional & Vocational Format: Paperback Publisher's Status: Active Availability: To order  Stock availability from the supplier is unknown. We will order it for you and ship this item to you once it is received by us. Table of Contents1. Mechanism and control of immunoglobulin gene rearrangement ; 2. T cell antigen recepotor genes ; 3. T lymphocyte signal transduction ; 4. Structure and function of MHC class I and class II antigens ; 5. Molecular mechanisms of antigen processing ; 6. B cell activation ; 7. Advances in antibody engineering ; 8. The complement systemReviewsIts chapters are written by leading experts, and the information is presented in a comprehensive yet direct manner. The most striking feature of the book is the number of references cited. Close to 2,000 publications, all with complete titles and authors, are referred to. . . . On the whole, presentations are even and well thought out. --Quarterly Review of Biology<br> An excellent second edition on important topics in molecular immunology. It covers in detail the generation and application of engineered antibodies and the molecular mechanisms of antigen presentation; immunoglobulin and T cell receptor rearrangements and expression; and the activation of B cells, T cells, and the complement cascade. The book incorporates contributions from recognized experts, most of whom work for academic research institutions in the U.S....Excellent and comprehensive. --Doody's Health Sciences Book Review<br> Listed in Books of Interest in Journal of Medicinal Chemistry<br> Its chapters are written by leading experts, and the information is presented in a comprehensive yet direct manner. The most striking feature of the book is the number of references cited. Close to 2,000 publications, all with complete titles and authors, are referred to. . . . On the whole, presentations are even and well thought out. --Quarterly Review of Biology An excellent second edition on important topics in molecular immunology. It covers in detail the generation and application of engineered antibodies and the molecular mechanisms of antigen presentation; immunoglobulin and T cell receptor rearrangements and expression; and the activation of B cells, T cells, and the complement cascade. The book incorporates contributions from recognized experts, most of whom work for academic research institutions in the U.S....Excellent and comprehensive. --Doody's Health Sciences Book ReviewListed in Books of Interest in Journal of Medicinal Chemistry Author InformationTab Content 6Author Website:Countries AvailableAll regions |
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