Overview

This Book Taught Me Everything. “This book gave me my foundation in biochemistry lab diagnostics. I 100% recommend this book to anyone who wants to learn about the different procedures…like (nucleic acid purification, nucleic acid amplification, expression testing, etc...)”—Ana, Online Reviewer Good book for CLS/MLT students.“Loved this book, I had the previous editions for college for my CLS/MTL classes. The book explains a lot and in great detail. Bought it again because I rented the other one and wanted a hard copy to study for the board.”—A.Y.Z.C., Online Reviewer Build the foundation for classroom and professional success. Meet the challenges of this rapidly expanding field with a solid understanding of the fundamentals of nucleic acid biochemistry as well as the advanced concepts integral to practice in today’s laboratories. With a focus on the application of molecular concepts to the diagnosis of disease, this popular resource encompasses microbiology, virology, genetics, oncology, and human identification. Inside, you’ll find in-depth explanations of the principles of molecular-based assays as well as reference material and trouble-shooting tips for the laboratory. Discussions of general diagnostic procedures prepare you to adapt to the emergence of new diagnostic technologies. New, Updated & Expanded! Incorporating advances in science and clinical practice and newer technologies and techniques New! Expanded descriptions of human identification for application to parentage testing, chimerism analysis, ancestry testing, and genetic genealogy Updated & Expanded! Coverage of basic genetics and DNA, proteins, cell function, managing and analyzing DNA data, next generation sequencing, polymerase chain reaction, primer designs, and more. New! Streamlined organization and a full-color design and art program to make often challenging concepts and techniques easier to understand New & Updated! Critical-Thinking Case Studies and Lab Exercises online Coverage of the application of molecular diagnostics to the clinical laboratory encompasses microbiology, virology, genetics, oncology, and human identification. “Advanced Concepts” challenge those interested in a higher level of learning. “Case Studies” in the clinical chapters show students how to apply molecular concepts to diagnostic testing. Study Questions at the end of each chapter (with answers in the Appendix) mirror the ASCP certification exam’s style.

Full Product Details

Author:   Lela Buckingham
Publisher:   F.A. Davis Company
Imprint:   F.A. Davis Company
Edition:   Fourth Edition
ISBN:  

9781719651134

ISBN 10:   1719651132
Pages:   504
Publication Date:   02 February 2026
Audience:   College/higher education ,  Tertiary & Higher Education
Format:   Paperback
Publisher's Status:   Forthcoming
Availability:   Not yet available  
This item is yet to be released. You can pre-order this item and we will dispatch it to you upon its release.

Table of Contents

Section I Fundamentals of Molecular Biology Chapter 1: Nucleic Acids Chapter 2: Genotype to Phenotype Chapter 3: Gene Expression and Epigenetics Section II Common Techniques in Molecular Biology Chapter 4: Collection, Isolation and Quantification of Nucleic Acids Chapter 5: Resolution and Detection of Nucleic Acids Chapter 6: Analysis and Characterization of Nucleic Acids and Proteins Chapter 7: Nucleic Acid Amplification Chapter 8: Human Chromosomal Structure and Structural Variants Chapter 9: Targeted Variant Detection Chapter 10: Molecular Sequencing Section III Molecular Techniques in the Clinical Laboratory Chapter 11: Molecular Variants and Human Identification Chapter 12: Detection and Identification of Microorganisms Chapter 13: Molecular Detection of Inherited Diseases Chapter 14: Molecular Oncology Chapter 15: DNA-Based Tissue Typing Chapter 16: Quality Assurance and Quality Control in the Molecular Laboratory Appendix A: Study Question Answers  Appendix B: Answers to Case Studies  Glossary  Index 

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Author Information

College of Health Sciences, Rush University Medical Center, Chicago, IL

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