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Author:   M. Feitelson
Publisher:   Kluwer Academic Publishers
Imprint:   Kluwer Academic Publishers
Edition:   1985 ed.
Volume:   6
Dimensions:   Width: 15.60cm , Height: 1.70cm , Length: 23.40cm
Weight:   1.290kg
ISBN:  

9780898386967

ISBN 10:   0898386969
Pages:   274
Publication Date:   31 January 1985
Audience:   College/higher education ,  Professional and scholarly ,  Postgraduate, Research & Scholarly ,  Professional & Vocational
Format:   Hardback
Publisher's Status:   Active
Availability:   In Print  
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Table of Contents

Hepatitis B Surface Antigen (HBsAg).- Nature of the “a” determinant.- Antigenic and immunogenic properties of HBsAg associated components.- Host components in HBsAg particles.- Possible vaccines lacking host components.- HBsAg associated carbohydrate.- HBsAg and the receptor for polymerized albumin.- Dane Particle “Specific” Antigenic Determinants.- Anti-HBs Monoclonal Antibodies.- Dane Particles and Hepatitis B Core Antigen (HBcAg).- Anti-HBc.- Hepatitis B e Antigen.- HBeAg and infectivity.- Chemical characterization.- HBeAg activity in Dane and core particles.- The Protein Kinase Activity in HBcAg and the Proposed Nucleic Acid Binding Properties of Core Polypeptide.- The DNA Polymerase Activity of HBV.- Characterization and relation to other polymerases.- Chemotherapy.- HBV Genome Structure and Expression.- General physical characteristics.- Restriction endonuclease analysis.- Genome isomers.- HBV in Hepatocellular Carcinoma and the Chronic Carrier State.- HBV DNA in human hepatoma cell lines.- HBV DNA in tumorous and nontumorous tissues.- Karyotyping of human hepatoma cells.- Nucleic Acid Sequencing of Dane Particle DNA and Expression of HBV Genes.- Nature of open reading frames.- Surface antigen gene structure and expression.- Core antigen and e antigen gene structure and expression.- The proposed polymerase gene of HBV DNA.- Open region X in HBV DNA.- The 5? Terminal Protein and Possible Origin of Genome Replication Associated with Hepatitis Viruses.- Replication Scheme for Hepatitis B and Related Viruses.- Conclusions.- References.

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